Objective The objective of this study was to assess the feasibility of using an intracameral phenylephrine/ketorolac infusion during cataract surgery as a single agent to prevent postoperative pain, inflammation, and other complications. Methods A prospective, single-group feasibility study was conducted in which phenylephrine/ketorolac infusion was administered during cataract surgery and no perioperative topical drops were initially prescribed. Patients underwent optical coherence tomography, corrected distance visual acuity testing, and slit lamp biomicroscopy examination at perioperative visits, during which they also reported symptoms of pain, irritation, and/or photophobia.
View Article and Find Full Text PDFPurpose: To describe a long-term outcome of a new technique using the femtosecond laser to assist with keratopigmentation (corneal tattooing).
Method: Nineteen eyes of 18 patients with a history of significant visual disability related to iris defects underwent femtosecond laser-assisted keratopigmentation (FAK) for functional restoration of their visual disabilities. Postoperative visual acuity and symptomatic resolution were collected during their postoperative visits.
Purpose: To evaluate the rate of cystoid macular edema development among cataract surgery patients on four different therapeutic regimens.
Methods: The present study is a retrospective analysis of 5,380 eyes following uncomplicated phacoemulsification at Wake Forest University. The study period went from July 2007 to December 2012.
Dysfunctional tear syndrome (DTS) is a common and complex condition affecting the ocular surface. The health and normal functioning of the ocular surface is dependent on a stable and sufficient tear film. Clinician awareness of conditions affecting the ocular surface has increased in recent years because of expanded research and the publication of diagnosis and treatment guidelines pertaining to disorders resulting in DTS, including the Delphi panel treatment recommendations for DTS (2006), the International Dry Eye Workshop (DEWS) (2007), the Meibomian Gland Dysfunction (MGD) Workshop (2011), and the updated Preferred Practice Pattern guidelines from the American Academy of Ophthalmology pertaining to dry eye and blepharitis (2013).
View Article and Find Full Text PDFPurpose: To describe a novel, small-incision, no-fold Descemet stripping automated endothelial keratoplasty (DSAEK) graft injector and to compare complications, visual acuity, and endothelial cell loss with a forceps technique.
Methods: An Institutional Review Board-approved, interventional, nonrandomized, consecutive case series analysis of 175 eyes undergoing DSAEK for Fuchs dystrophy and bullous keratopathy. The injector arm is prospective, and the forceps arm is retrospective.
Purpose: To report a Descemet stripping automated endothelial keratoplasty (DSAEK) insertion technique using sodium hyaluronate (Healon) and describe complication rates, visual acuity, and endothelial cell counts.
Methods: A retrospective analysis of 105 eyes in 91 patients undergoing DSAEK. Ninety-three eyes had Fuchs endothelial dystrophy, 11 had bullous keratopathy, and 1 had iridocorneal endothelial (ICE) syndrome.
Corneal transplantation is a common transplant procedure performed to improve visual acuity by replacing the opaque or distorted host tissue by clear healthy donor tissue. However, its clinical utility is limited due to a lack of high quality donor corneas. Bioengineered neo-corneas, created using an expandable population of human donor-derived corneal endothelial cells (HCEC), could address this current shortage.
View Article and Find Full Text PDFJ Cataract Refract Surg
March 2006
Purpose: To describe a novel method for calculating intraocular lens (IOL) power after myopic laser in situ keratomileusis (LASIK) without using the inaccuracies of the post-LASIK corneal power.
Setting: Department of Ophthalmology, Wake Forest University Eye Center, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.
Methods: This retrospective chart review comprised 9 eyes of 9 patients who had phacoemulsification after LASIK using our method for IOL calculation.
Eye Contact Lens
January 2006
Purpose: To describe a case of Acanthamoeba keratitis that resulted from a cosmetic contact lens purchased from an unlicensed vendor.
Methods: Case report.
Results: A 26-year-old man developed Acanthamoeba keratitis from a cosmetic contact lens and ultimately required a penetrating keratoplasty.
J Cataract Refract Surg
April 2004
Purpose: To determine whether environmental factors affect laser in situ keratomileusis (LASIK) enhancement rates.
Setting: Wake Forest University Eye Center, Winston-Salem, North Carolina, USA.
Methods: This retrospective chart review comprised 368 consecutive eyes of 191 myopic patients who had LASIK by the same surgeon (K.
Purpose: To describe the ocular surface injury resulting from a microwave superheated liquid.
Methods: Case report.
Results: A 40-year-old man sustained an ocular surface injury from a microwave superheated liquid.