Meiotic recombination is a key evolutionary process that generates novel allele combinations during prophase I of meiosis, promoting genetic diversity and enabling the selection of desirable traits in livestock breeding. Although its molecular mechanisms are well-characterised in model organisms such as humans and mice, studies in African indigenous cattle, particularly South African breeds, remain scarce. Key regulators of recombination, including , , and , play essential roles in crossover formation and genome stability, with mutations in these genes often linked to fertility defects.
View Article and Find Full Text PDFDue to its high digestibility, rich nutrient profile, and potential probiotic content, goat milk is an essential nutritional resource, particularly for individuals with cow milk allergies. This review summarises the current state of microbial diversity in goat milk, emphasising the implications for quality, safety, and probiotic potential. This systematic review adhered to PRISMA guidelines, conducting a comprehensive literature search across PubMed, ScienceDirect, and Google Scholar using keywords related to microbial profiling in goat milk.
View Article and Find Full Text PDFGoats play a vital role in global livestock systems, particularly in developing regions, where they contribute significantly to meat production and smallholder livelihoods. Indigenous goats in sub-Saharan Africa are essential to low-input farming systems, valued for their adaptability to harsh environments and their provision of meat, milk, and income. However, genomic research on these goats remains limited despite their importance.
View Article and Find Full Text PDFGoat milk has gained recognition for its medicinal, cosmetic, and health benefits, particularly its potential to improve human skin conditions. Its therapeutic properties are attributed to bioactive compounds influenced by genes such as (), (), and (), known for their antimicrobial, immunomodulatory, and anti-inflammatory effects. Genetic factors are hypothesized to shape goat milk's composition and its effectiveness in managing dermatological conditions like eczema and psoriasis.
View Article and Find Full Text PDFGrowth and carcass quality are economically important traits in goat production. This study investigated differentially expressed genes from the caprine pituitary gland transcriptome of South African indigenous goat breeds of varying growth performances and carcass quality parameters. Tissues were harvested from the pituitary gland of three South African Boer goats and three village ecotype goats all raised under similar conditions simulating intensive commercial production systems.
View Article and Find Full Text PDFCarcass quality includes a battery of essential economic meat traits that play a significant role in influencing farmer breed preferences. A preliminary study was undertaken to investigate the carcass quality and the associated genomic regions in a small nucleus of animals that are representative of South African goat genetic resources. Samples of the South African Boer ( 14), Northern Cape Speckled ( 14), Eastern Cape Xhosa Lob ear ( 12), Nguni/Mbuzi ( 13), and Village ( 20) were genotyped using the Illumina goat SNP50K and were phenotyped for carcass quality traits.
View Article and Find Full Text PDF