Publications by authors named "Kaylee D Rich"
Article Synopsis
- Pathogens use sophisticated strategies like molecular mimicry to manipulate host signaling pathways.
- In this study, researchers developed a bioinformatics pipeline to identify molecular mimicry between human proteins and those of 32 pathogenic species, finding that fungi and protozoans had more mimicry candidates than bacteria.
- The analysis uncovered 1,878 mimicked regions in 1,439 human proteins, highlighting their potential role in biological processes, particularly in extracellular matrix organization, while noting that immune-related proteins were less frequently targeted.
- This research enhances our understanding of host-pathogen interactions and could aid in developing new therapeutic strategies.
