Exposure to bisphenol S promotes renal damage via aryl hydrocarbon receptor and NF-κB pathways in a mice model of obesity.

Objective: To investigate the impact of bisphenol S (BPS) exposure on kidney function parameters, renal histopathology, and inflammatory markers in mice that received a high-fat diet.

Methods: 43 male C57BL/6 mice were divided into control (C; n = 9), high-fat diet (HF; n = 10), control + BPS (CBPS; n = 12), and high-fat diet + BPS (HFBPS; n = 12) groups. The drinking water offered BPS (25 μg/kg body mass/day).

Immunohistochemical identification of ACE-2 (SARS-COV II entry mechanism) in the gastrointestinal tract, kidney and lung of rhesus monkeys (Macaca mulatta) and squirrel monkeys (Saimiri sciureus).

SARS-Cov-2 is a corona virus that causes COVID-19 disease, a viral infection responsible for the pandemic decreed by the World Health Organization in March 2020. Angiotensin-converting enzyme 2 (ACE-2) functions as the main receptor for SARS-Cov-2. The study aimed to detect the expression of ACE-2 in the gastrointestinal tract, kidney, and lung in the rhesus monkeys and squirrel monkeys.