Publications by authors named "Kaspar Pohl"
Clinical management of oligometastatic cancer: Applying multidisciplinary tumor board recommendations in practice.
Clin Transl Radiat Oncol
September 2024
Aims: Multidisciplinary tumor boards (MDTs) are an integral part of ensuring high-quality, evidence-based and personalized cancer care. In this study, we aimed to evaluate the adherence to and implementation of MDT recommendations in patients with oligometastatic disease (OMD).
Methods: We screened all oncologic positron emission tomography (PET) scans conducted at a single comprehensive cancer center in 2020.
Article Synopsis
- - The study explores the continuum of metastatic disease, aiming to quantify the tumor burden and patterns of spread in patients referred for PET scans, revealing a complex relationship between the number of metastases and their organ distribution.
- - Analysis of over 7,000 PET scans showed that 33% of patients had metastatic disease, with about half classified as oligometastatic (max 5 metastases) and half as polymetastatic (over 5 metastases), displaying common primary tumors like lung and breast cancers.
- - Findings indicate that many patients either have a solitary metastasis or a high tumor burden (>10 metastases), but those with multiple metastases often have them concentrated in one or two organs, supporting existing theories of metast
Recognition of and treatment recommendations for oligometastatic disease in multidisciplinary tumor boards.
Clin Transl Radiat Oncol
January 2023
Background And Introduction: Growing evidence supports a combined modality treatment strategy for patients with oligometastatic disease. However, lack of phase III trial data and uncertainties around patient selection highlight the importance of multidisciplinary tumor boards (MDT) in therapeutic decision-making. This study aimed to analyze the recognition of and treatment recommendations for oligometastatic patients by MDTs at a large comprehensive cancer center in order to better understand current treatment patterns of oligometastasis.
View Article and Find Full Text PDFImaging-Based Prevalence of Oligometastatic Disease: A Single-Center Cross-Sectional Study.
Int J Radiat Oncol Biol Phys
November 2022
Purpose: Oligometastatic disease refers to a distinct state in patients with cancer characterized by a low metastatic burden, with diagnosis being informed by a limited number of distant metastases in radiologic imaging. However, oligometastasis remains poorly understood in terms of its biology and prevalence in the metastatic cascade. In the absence of clinically viable molecular biomarkers, this study examined the prevalence of oligometastasis using oncological imaging.
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