Role of the FDG PET CT Scan in Pretreatment Evaluation of Oral Carcinomas.

Pre-treatment role of FDG PET CT scan to evaluate- the extent of the primary lesion, nodal staging and distant metastasis in oral carcinoma in various TNM stages. Additionally, our study investigated the Correlation between SUVmax values on FDG-PET CT scans and histopathological proven positive nodes in patients undergoing surgery. In this study, all suspected cases of oral carcinoma in adults who visited the ENT clinic were examined and evaluated using various methods, including clinical examination, cytology, histopathology, and imaging tests like CECT scans, ultrasound, and CEMRI.

Versatility of Islanded Nasolabial Flap Based on Facial Artery and Vein for Reconstruction of Oral Cancer Defects, Experience in a Tertiary Care Center.

Introduction: Conventional nasolabial flap has been widely used for reconstruction for head and neck defects. Recent decades witnessed modification of this flap like islanded version based on subcutaneous pedicle or facial artery and vein. The later modification obviated a need for pedicle division, secondary procedures and facilitates reach of the flap to distant sites.

Trotter Procedure with Harmonic Scalpel : A Unique Approach to Mucoepidermoid Carcinoma of Tongue Base Revisited.

Mucoepidermoid carcinoma (MEC) is a malignant locally invasive tumour of salivary glands, presumed to arise from reserve cells of salivary gland ducts. It accounts approximately 35% of all malignancies of major and minor salivary glands [1]. MEC arising in minor salivary glands can be located in different areas such as palate, retromolar trigone, floor of mouth, buccal mucosa, lips and tongue.

Alcohol-Containing Mouthwash and the Risk of Oral Cancer: Exploring the Association.

Oral cavity and larynx cancers are generally associated with tobacco consumption, alcohol abuse or both. Mouthwashes are liquid antiseptic solutions that decrease the microbial load in the oral cavity. Alcohol is often used in mouthwashes for its antiseptic functions and as a carrier for some active ingredients, including menthol or thymol, helping them penetrate the plaque.

Artificial neural network to predict post-operative hypocalcemia following total thyroidectomy.

Unlabelled: The primary objective of this study was to use artificial neural network (ANN) to predict the post operative hypocalcemia and severity of hypocalcemia following total thyroidectomy. The secondary objective was to determine the weightage for the factors predicting the hypocalcemia with the ANN. A single center, retrospective case series included treatment-naive patients undergoing total thyroidectomy for benign or malignant thyroid nodules from January 2020 to December 2022.

Endoscopic Sellar Defect Reconstruction with Avascular Modified Gasket Seal Technique for Sellar Tumors.

Watertight repair of the skull base defect is necessary during endonasal skull base surgery to avoid postoperative CSF leak (poCSFl) and consequent intracranial complications. Various techniques have been described for reconstructing sphenoid-sellar defects with varying success rates. We have described the immediate and long-term outcomes following the reconstruction of sphenoid-sellar defects with our technique.

NLP AI Models for Optimizing Medical Research: Demystifying the Concerns.

Natural language processing (NLP) AI models have gained popularity in research; however, ethical considerations are necessary to avoid potential negative consequences. This paper identifies and explores the key areas of ethical concern for researchers using NLP AI models, such as bias in training data and algorithms, plagiarism, data privacy, accuracy of generated content, prompt and content generation, and training data quality. To mitigate bias, researchers should use diverse training data and regularly evaluate models for potential biases.

Standardizing the Head and Neck Cancer Treatment and Research.

Head and neck cancer requires a multidisciplinary approach, with standardized care being essential for consistent, high-quality treatment. Standardization involves evidence-based guidelines and protocols, and collaboration is necessary for research and improving outcomes. However, collaboration can be challenging due to various barriers.

Emergency Tracheostomy in Locally Advanced Anaplastic Thyroid Cancer.

Over 30% of cases may present with acute airway obstruction due to anaplastic thyroid cancer (ATC). In such situations, performing an emergency tracheostomy may be mandatory to save the life. A retrospective, single-centre study at our centre was conducted between 1 January 2021 to 31 December 2022.

Observational Learning in Surgical Skill Development.

Observation plays a key role in the development of surgical skills, as it allows trainees to learn from experts and improve their performance through trial-and-error practice. This process, known as motor learning, involves the creation of new neural pathways that enable precise control of surgical instruments through hand movements. In recent years, there has been a shift towards minimally invasive surgery, which requires surgeons to continually learn new motor skills to control specialized instrumentation.

Survival Outcomes in T3 Laryngeal Cancers: Primary Total Laryngectomy vs. Concurrent Chemoradiation or Radiation Therapy-A Meta-Analysis.

Background: The management of cT3 laryngeal cancers remains controversial, with studies recommending surgical or non-surgical approaches. Despite the many papers that have been published on the subject, there is a lack of studies showing which treatment has better results in terms of survival.

Objective: To determine the difference in survival outcomes following total laryngectomy (TL), concurrent chemoradiation (CRT) or radiation therapy (RT) alone in T3 laryngeal cancers.

Pharyngocutaneous Fistula Following Primary Total Laryngectomy: a Meta-analysis.

Unlabelled: Pharyngocutaneous fistula (PCF) is the most common complication which significantly increases morbidity. High-level evidence is lacking that determines the PCF rates in the primary laryngectomy. The main objective of this study was to systematically identify the factors leading to the PCF formation in primary laryngectomy.

Correction to: Molecular Insights into Oral Malignancy.

[This corrects the article DOI: 10.1007/s13193-021-01431-4.].

Molecular Insights into Oral Malignancy.

Squamous cell carcinoma constitutes around 95% of malignancies in the oral cavity. The 5-year overall survival has not substantially improved for oral cancers over the last few decades, despite several advances in diagnosis, imaging, and treatment modalities. With progressive improvement in knowledge of the molecular pathways, cancer therapy can now be individualized.

Revision Thyroid Surgery.

The incidence of recurrence in well-differentiated thyroid malignancies range from 10 to 30%. It is estimated that about 31-46% of patients with differentiated thyroid cancer will have the persistent disease and 1.2-6.

Free Flap Reconstruction and Its Management in Sickle Cell Trait: Lessons Learned from a Case.

Oral cancers are amongst the most common cancers in the Indian subcontinent; in India alone, an estimated 1.2 lakh new patients were diagnosed with it. Reconstruction with free flaps slowly gained popularity over time to become the standard for care for treating large head and neck defects.

Multidisciplinary Management of COVID-Associated Mucormycosis Syndemic in India.

Unlabelled: The study aimed to determine clinical presentation, contributing factors, medical and surgical management, and outcome of patients with coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM). A cross-sectional, single-center study was conducted on patients receiving multidisciplinary treatment for mucormycosis following the second wave of COVID-19 pandemic from April to June 2021 in India. Clinicoepidemiological factors were analyzed, 30-day overall survival and disease-specific survival were determined, and -test was used to determine the statistical significance.