Modulation of Inflammation in McCoy Cells by Zinc Nanoparticles Conjugated With β-Chitosan.

Introduction: This study investigated biosynthetically derived β-chitosan-derived zinc nanoparticles (β-Ch-Zn NPs) for their potential anti-inflammatory properties on McCoy cells. β-Ch-Zn NPs were synthesized using a green chemistry approach, and their characterization confirmed successful synthesis, appropriate size, and morphology. The study aimed to evaluate the cytotoxicity of β-Ch-Zn NPs and their effects on inflammatory responses in McCoy cells stimulated with lipopolysaccharide (LPS).

Advanced Dental Care: β-Chitosan Zinc Oxide Nanoparticles Targeting Cariogenic Microorganisms.

Introduction Dental caries, primarily caused by cariogenic microorganisms, remains a significant global health concern. β-Chitosan, known for its biofilm-targeting properties, and zinc oxide (ZnO) nanoparticles (NPs), recognized for their potent antimicrobial effects, offer a promising approach for caries prevention and treatment. This study investigates the synthesis, characterization, and antimicrobial properties of β-Chitosan-derived ZnO NPs (β-Ch-ZnO-NPs) against these pathogens.

Histologic Assessment of a Fast-Set Mineral Trioxide Aggregate (MTA) and Two Novel Antibacterial-Enhanced Fast-Set MTAs for Apexification and Periapical Healing of Teeth With Incomplete Root Formation in a Rat Model: An In Vivo Animal Study.

Background Pulp necrosis in incomplete root formation halts dentine development, resulting in larger canals with fragile walls and an open apex, complicating canal instrumentation and apical stop formation. Bioactive endodontic cements such as mineral trioxide aggregate (MTA) are crucial for creating artificial apical barriers or inducing apical foramen closure, but challenges remain regarding their antimicrobial efficacy and cytotoxicity. Modifications to MTA formulations aim to address these concerns.

Assessment of Toxicity of Green Synthesized Silver Nanoparticle-coated Titanium Mini-implants with Uncoated Mini-implants: Comparison in an Animal Model Study.

Aim: To assess the potential for systemic toxicity when silver nanoparticle-coated mini-implants were implanted in Wistar albino rats conducted as a comparative study in the animal model by assessing the blood biochemistry, liver and kidney function, and histology of the implanted site.

Materials And Methods: The surface of the mini-implant was coated with a green-mediated silver nanoparticle. Uncoated mini-implants were placed in two groups of eight Wistar albino rats, and silver nanoparticle-coated mini-implants were placed in another eight rats.

Role of individual and combined impact of simvastatin and α-TCP in rat calvarial bone defect: An experimental study.

Background: Bone substitutes have been used by doctors for a long time to treat osseous abnormalities. Recently, scientists have been searching for suitable materials to replace bone. Autogenous bone grafts are considered the gold standard for osseous regeneration.

Efficacy of Graphene-Based Nanocomposite Gels as a Promising Wound Healing Biomaterial.

The development of biocompatible nanocomposite hydrogels with effective wound healing/microbicidal properties is needed to bring out their distinguished characteristics in clinical applications. The positive interaction between graphene oxide/reduced graphene oxide (GO/rGO) and hydrogels and aloe vera gel represents a strong strategy for the advancement of therapeutic approaches for wound healing. In this study, the synthesis, characterization, and angiogenic properties of graphene-based nanocomposite gels have been corroborated and substantiated through several in vitro and in vivo assays.

Morphometric analysis of oculomotor triangle in dry human skulls and its clinical applications.

The oculomotor triangle is denoted as the "Triangle of Hakuba" or the "Hakuba's Triangle." This oculomotor triangle is a significant anatomical landmark. Oculomotor nerve, abducens nerve and part of the internal carotid artery (ICA) lie in this triangle.

Morphometric analysis of Bonwill's triangle and its dental applications in dry human mandible bones.

Bonwill's triangle is an imaginary equilateral triangle formed when the centers of two condyles and each condyle with the medial mandibular incisal midpoint are joined. The dimensions of the tooth, with other bones of cranium, and the entire anatomical structure of body are in persistent association with the distance of the borders of the triangle. It can be used to study articulation of the mandible, complete dentures, and dental occlusion and can be related when treating mandibular fractures.

Therapeutic potential of (Linn.) on high-fat diet-induced testicular and sperm damage in rats.

Objective: Linn., a leguminous plant, is identified as a herbal medicine for improving fertility-related disorders in the alternative and complementary systems of medicine. The study was focused on evaluating the therapeutic potential of on testis and sperm parameters in a high-fat-induced hypercholesterolemia model.

Therapeutic potential of (Linn.) on ageing induced damage in dorsal nerve of the penis and its implication on erectile function: an experimental study using albino rats.

Objective: To study the effect of ethanolic seed extract of on damaged dorsal nerve of the penis (DNP) in aged rat in relation to penile erection.

Methods: The rats were divided into four groups Young (3 months), Aged (24 - 28 months), Aged +  and Young +  (200 mg/kg b.w/60 days) and were subjected to the hypophysial - gonadal axis, nerve conduction velocity (NCV), and penile reflex.