Publications by authors named "Karoline Medeiros"
Objective: Determining the etiology of hyperprolactinemia is fundamental for selecting the most appropriate treatment strategy. The aim of this study was to evaluate the usefulness and accuracy of prolactin levels in predicting the etiology of nonphysiological hyperprolactinemia.
Subjects And Methods: In this retrospective study, we reviewed medical records of patients with nonphysiological hyperprolactinemia seen at two neuroendocrine reference centers located in Recife, Brazil, from January 2000 to December 2019.
Long COVID: plasma levels of neurofilament light chain in mild COVID-19 patients with neurocognitive symptoms.
Mol Psychiatry
October 2024
Article Synopsis
- The study explores the link between high plasma levels of neurofilament light chain (pNfL) and neurocognitive symptoms in patients with Long COVID, indicating that SARS-CoV-2 can lead to long-term brain effects even after mild illness.
- A group of 63 Long COVID patients underwent neurocognitive assessments, revealing that those with cognitive issues and fatigue had significantly higher pNfL levels compared to those without these symptoms.
- The findings suggest that measuring pNfL could help identify individuals at risk for CNS involvement and guide their need for ongoing monitoring and treatment for neurocognitive dysfunction post-COVID.
By the year 2050, the world's elderly population may increase exponentially, raising the rate of disease characteristic of this group, such as prostate cancer (PCa) and benign prostatic hyperplasia (BPH). Prostate disorders have a multifactorial etiology, especially age and genetic factors. Currently, PCa is the second most frequent neoplasm in the male population worldwide.
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- The study focuses on the role of preoperative cytology in assessing thyroid nodules and how it relates to risks of mortality, recurrence, and tumor aggressiveness.
- The research involved a retrospective analysis of 153 patients with differentiated thyroid carcinoma, finding a majority were female and the common diagnosis was papillary carcinoma.
- Results showed a significant link between preoperative fine-needle aspiration results and aggressive tumor features, highlighting the need for further research with larger sample sizes to validate these findings.