Arginine-Tryptophan Peptides Enhancing Antibacterial and Anticancer Effects of Ruthenium(II) Polypyridyl Complex Photosensitizers.

In recent years, photodynamic therapy (PDT) has emerged as a potential antibacterial and anticancer alternative. The free radicals are generated in the presence of photosensitizers (PS) and oxygen under light irradiation of a specific wavelength, causing cytotoxic damage to the cells. Ruthenium-(II) photosensitizers (Ru-(PS)) are of interest due to their rich photochemical properties and potential antibacterial and anticancer activities reported in previous studies.

1,2,3-Triazol-5-ylidene- 1,2,3-triazole-based tricarbonylrhenium(I) complexes: influence of a mesoionic carbene ligand on the electronic and biological properties.

The tricarbonylrhenium complexes that incorporate a mesoionic carbene ligand represent an emerging and promising class of molecules, the solid-state optical properties of which have rarely been investigated. The aim of this comprehensive study is to compare three of these complexes with their 1,2,3-triazole-based analogues. The Hirshfeld surface analysis of the crystallographic data revealed that the triazolylidene derivatives are more prone to π-π interactions than their 1,2,3-triazole-based counterparts.

Ruthenium(II) polypyridyl complexes as emerging photosensitisers for antibacterial photodynamic therapy.

Photodynamic therapy (PDT) has recently emerged as a potential valuable alternative to treat microbial infections. In PDT, singlet oxygen is generated in the presence of photosensitisers and oxygen under light irradiation of a specific wavelength, causing cytotoxic damage to bacteria. This review highlights different generations of photosensitisers and the common characteristics of ideal photosensitisers.