Field Marigold (Calendula arvensis L.) accelerates wound-healing in vivo: role of transforming growth factor-beta1 (TGF-β1), inflammatory, and biochemical molecules.

Medicinal plants are major sources of natural products, which have gained a renewed interest in recent years because of drawbacks associated with synthetic ones used for human health disorders. Calendula arvensis L. is a traditional medicinal plant used for many inflammatory-related diseases.

Short path molecular distillation of the essential oil from oleoresin affords volatile fractions with powerful antioxidant and antimicrobial activities comparable with common synthetic agents and antimicrobials.

The primary purposes of this work were to study the influence of the distillation temperature on the yield of the turpentine essential oil hydrodistilled from the oleoresin and to obtain products with powerful bioactivities by short path molecular distillation of the oil. Our findings showed that the hydrodistillation temperature affected the yield as well as the antioxidant and antimicrobial properties of the essential oil: the highest yield (20.27 %) and bioactivities were obtained for the oil distilled at 180 °C.

A New Glucosyl Flavone with Inhibitory Activity of Cancer Cell Viability and Other Bioactive Constituents from the Traditional Kurdish Plant L.

A new glucosyl flavone, 5,7,2',5'-tetrahydroxyflavone 7--β-d-glucopyranoside, named loeflingiin, together with apigenin 6--glucoside (isovitexin), coumarins citropten and isompinellin, triterpenoids betulin and betulinic acid, and a mixture of phytosterols β-sitosterol, stigmasterol and campesterol were isolated for the first time from the leaves of wild L. () collected in the Iraqi Kurdistan region. The plant is used by local people to treat wounds and as a vulnerary remedy.