Toxic metals and bioelements: Combined oxidative stress effects on liver injury and thyroid hormone disruption in subjects from different areas of Erbil province.

In Iraq, particularly in Erbil city and Gwer road are deemed environmentally disadvantaged because of industrial pollutants and refinery activities. This study conducted 143 subjects from rural, urban, and industrial areas. The sera of subjects were taken for the analysis.

Impact of Industrial Pollution on Human Renal Function and Male Reproductive Hormones: An Investigation of Heavy Metals Toxicity and Oxidative Stress.

Industrial pollution provides significant public health risks through exposure to heavy metals (HMs). This study assessed serum HMs (Cd, Cr, Ni, Sn, Zn, and B), oxidative stress (OS) markers, renal function biomarkers, and male reproductive hormones in 135 participants across rural, urban, and industrial areas (Erbil Province, Iraq), using ICP-MS, ELISA, and automated immunoassays. Industrial workers showed significantly elevated HMs concentration, particularly for Cd [industrial: 0.

Acute toxicity and hepatoprotective effect of on rat liver cirrhosis induced with thioacetamide.

is a medicinal plant that has been employed in traditional medicine for treating liver diseases. The objective of the current study was to evaluate the hepatoprotective impacts of ethanolic extract of the leaves on cirrhosis induced by thioacetamide (TAA) in Sprague--Dawley rats. The rats were treated for two months with thioacetamide (TAA) administered intraperitoneally thrice weekly.

Chemical Composition and In Vitro Evaluation of Antioxidant and Antiproliferative Effects of Volatile Oils Hydrodistilled from C.C. Towns., a Kurdish Traditional Plant.

The volatile oils hydrodistilled from the aerial parts and roots of C.C Towns. (Fabaceae) have been chemically characterized for the first time.

Anti-ulcer effect of on absolute alcohol-induced stomach ulceration.

() has been reported to have a numeral of biological properties. Though, the influence of this plant extract on stomach ulceration is yet stated. Thirty rats arbitrarily alienated 5 groups: the normal group, the ulcerated control group, the omeprazole group, and 2 investigational groups.

Oxidation and nitrosylation of cysteines proximal to the intermediate filament (IF)-binding site of plectin: effects on structure and vimentin binding and involvement in IF collapse.

As an intermediate filament (IF)-based cytolinker protein, plectin plays a key role in the maintenance of cellular cytoarchitecture and serves at the same time as a scaffolding platform for signaling cascades. Consisting of six structural repeats (R1-6) and harboring binding sites for different IF proteins and proteins involved in signaling, the plectin C-terminal domain is of strategic functional importance. Depending on the species, it contains at least 13 cysteines, 4 of which reside in the R5 domain.