Overlap Syndrome of Cogan's and Tubulointerstitial Nephritis and Uveitis (TINU) in a Case with Uveitis, Hearing Loss, and Kidney Involvement.

Purpose: Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare autoimmune disorder characterized by concurrent renal and ocular inflammation. Auditory features resembling Cogan's syndrome have been reported in TINU, though the nature of this overlap remains poorly understood. Here, we report a pediatric case of atypical Cogan syndrome to contribute to the growing literature on this unusual clinical association.

The day that belongs to children.

This article discusses a national holiday in Türkiye, dedicated to children and democracy, and how its celebration in a hospital setting serves as a vital moment of healing and joy for hospitalized children, reaffirming their identity beyond illness and underscoring the societal commitment to protect and celebrate childhood. We aimed to reflect this through the lens of a pediatrician to raise awareness and inspire healthcare professionals regarding the emotional nurturing practices in clinical settings. It may influence policymakers or hospital administrators to support similar celebratory and therapeutic initiatives, recognizing the role of emotional well-being in pediatric recovery.

The Potential of ChatGPT as a Source of Information for Kidney Transplant Recipients and Their Caregivers.

Background: Education and enhancing the knowledge of adolescents who will undergo kidney transplantation are among the primary objectives of their care. While there are specific interventions in place to achieve this, they require extensive resources. The rise of large language models like ChatGPT-3.

Severe haematological involvement in children with systemic lupus erythematosus and clinical associations.

Objectives: To investigate the severe haematological involvement in children with SLE and assess its clinical associations, treatments, outcome and damage accrual.

Methods: The medical charts of children with SLE in whom haematological involvement was observed were reviewed. Severe haematological indices were defined as autoimmune haemolytic anaemia with a haemoglobin concentration <8 g/dl, thrombocyte count <30 000/µL and neutrophil count <500/µL.

Factors affecting medical students' satisfaction with online learning: a regression analysis of a survey.

Background: Medical education requires the implementation of different teaching methods and strategies for future doctors to achieve broad learning objectives. This wide range of methods and strategies includes the use of Information Technologies. For a long time, there was a call for a change in medical education for blending new teaching approaches to lessen medical students' class time.

Clinical and subclinical acute kidney injury in children with mild-to-moderate COVID-19.

Background: Our aim was to identify acute kidney injury (AKI) and subacute kidney injury using both KDIGO criteria and urinary biomarkers in children with mild/moderate COVID-19.

Methods: This cross-sectional study included 71 children who were hospitalized with a diagnosis of COVID-19 from 3 centers in Istanbul and 75 healthy children. We used a combination of functional (serum creatinine) and damage (NGAL, KIM-1, and IL-18) markers for the definition of AKI and subclinical AKI.

Tocilizumab in COVID-19: The Cerrahpaşa-PREDICT score.

Background: Cytokine release syndrome (CRS), characterized by overproduction of proinflammatory cytokines in the course of severe coronavirus disease 2019 (COVID-19), has been suggested as the major cause of mortality. Tocilizumab, a recombinant humanized monoclonal antibody against human IL-6 receptor, poses a therapeutic option for the treatment of CRS leading to severe acute respiratory syndrome in coronavirus-2 (SARS-CoV-2) infection.

Methods: We performed a single-center retrospective study to reveal the outcome of COVID-19 patients on tocilizumab and proposed "the Cerrahpaşa-PREDICT score", a new clinical scoring system using clinical and laboratory parameters that would help predicting the 28-day mortality of COVID-19 patients receiving tocilizumab.