Physiological costs of infection by the invasive parasitic copepod Mytilicola intestinalis accumulate across temporal scales in the blue mussel Mytilus edulis.

Exploitation of host resources by parasites can have profound impacts on infected hosts. When prevalence is high parasite infection can even feed back on host population dynamics. Especially when parasites are invasive species, their new native hosts can suffer from exploitation due to a lack of co-evolutionary history.

Hydrothermal microwave synthesis of water soluble NIR-II emitting AgS quantum dots.

Hydrothermal-based synthetic methods of quantum dots allow for the exploration of reaction parameters normally inaccessible to typical aqueous-based batch reactions, such as elevated reaction temperatures (>100 °C) and reaction pressures above atmospheric pressure. Coupled with microwave heating, new instantaneously bio-compatible quantum dots (QDs) with enhanced opitcal properties can be yielded. As of today, aqueous-based synthetic methods often lag behind their organic analogues in terms of the photophysical properties of the QDs obtained and the ease of modulation of both the emission wavelength and crystallite size.

Separation of Indium Phosphide/Zinc Sulfide Core-Shell Quantum Dots from Shelling Byproducts through Multistep Agglomeration.

Semiconductor quantum dots (QDs) possess unique electronic and optical properties, making them promising candidates for applications in light-emitting diodes, solar cells, bioimaging, and photocatalysis. Precise control over their size, shape, and chemical and electronic structure is crucial to ensure the desired functional properties and optimize device performance. However, challenges in QD synthesis and post-synthesis modification persist, especially in large-scale production.

are a potential source of novel colistin-resistance genes in European coastal environments.

Colistin is a widespread last resort antibiotic for treatment of multidrug-resistant bacteria. The recent worldwide emergence of colistin resistance (Col-R) conferred by -1 in human pathogens has raised concern, but the putative sources and reservoirs of novel genes in the marine environment remain underexplored. We observed a high prevalence of Col-R, particularly in isolated from European coastal waters by using the same cohorts of oysters as bioaccumulators in three sites across Europe.

NIR-II aza-BODIPY Platform for the Development of a Fluorescent Antibody Drug Conjugate.

Real-time imaging of antibody-drug conjugates (ADCs) offers valuable insights for assessing tumor targeting specificity, monitoring therapeutic efficacy, and detecting off-target accumulation that may cause adverse effects. To enable precise tracking, we developed a versatile fluorescent platform based on an NIR-II emitting aza-BODIPY dye, which can be site-specifically grafted onto an IgG1 antibody to generate well-defined fluorescent ADCs. As a proof of concept, we synthesized an HER2-targeting trastuzumab immunoconjugate bearing a NIR-II aza-BODIPY fluorophore.