Publications by authors named "Jun-Lin Zhao"
Background: Pediatric acute liver failure (PALF) is a life-threatening condition with no definitive treatment. This study evaluated the combined use of the dual plasma molecular adsorption system (DPMAS) and plasma exchange (PE) to improve liver function and survival outcomes in PALF patients.
Methods: A retrospective study was conducted on 7 PALF patients treated with DPMAS and PE.
Article Synopsis
- The study focused on the effectiveness of using a combined blood purification method (haemoperfusion + continuous venovenous haemodiafiltration) to treat children with severe viral encephalitis, while also examining cerebrospinal fluid neopterin levels as a prognostic indicator.
- Researchers compared treatment outcomes among three groups of children: those receiving combined treatment, those receiving only CVVHDF, and those with mild encephalitis not treated with blood purification.
- Results showed that while there was no significant difference in some clinical outcomes, higher CSF neopterin levels were linked to more severe brain lesions and poorer motor functions, suggesting the potential for this blood purification method to improve treatment in severe cases
Gastric cancer (GC) is the second most frequent oncological cause of death, the fifth most common malignancy in the world, and accounts for 6.8% of all tumors. As an aggressive disease, GC is often diagnosed at an advanced stage, which is why it is a major cause of cancer-related death.
View Article and Find Full Text PDFImmunopathogenesis of Colitis-Associated Cancer in an Animal Model.
Crit Rev Eukaryot Gene Expr
August 2016
Chronic inflammation, such as that seen in patients with inflammatory bowel disease (IBD), greatly increases the risk of developing colon cancer. Growing evidence supports a role for T cell-mediated immune response and release of various cytokines in the pathogenesis of colitis-associated cancer (CAC). In fact, CD4+ effector T cells promote chronic inflammation associated with IBD through release of proinflammatory cytokines, which leads to initiation and progression of colon cancer.
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