BTP2 restricts Tulane virus and human norovirus replication independent of store-operated calcium entry.

Human norovirus is the leading cause of viral gastroenteritis across all age groups. While there is a need for human norovirus antivirals, therapeutic development has been hindered by a lack of cell culture systems and animal models of infection. Surrogate viruses, such as Tulane virus (TV), have provided tractable systems to screen potential antiviral compounds.

Draft genome sequences of sp. MMG031 and sp. MMG032 isolated from the dinoflagellate .

Here, we report the draft genome sequences of sp. MMG031 and sp. MMG032, isolated from coral-associated dinoflagellate , assembled and analyzed by undergraduate students participating in a Marine Microbial Genomics (MMG) course.

[Cytogenetic and molecular profile of genetic diseases in Puerto Montt main hospital].

Background: Chromosome aberrations (CA) are the main etiology of multiple congenital malformations, recurrent abortions and intellectual disability (ID) specifically of moderate and severe degree. They account for 0.3 to 1% of newborns (NB) and 6 of 10,000 NB have chromosome imbalances with submicroscopic deletions or duplications smaller than 10 MB that are overlooked by conventional cytogenetic studies.

Transcatheter closure of large patent ductus arteriosus at high altitude with a novel nitinol device.

Background: Patent ducti arteriosi (PDAs) are more frequent and larger at high altitude than at sea level. A novel PDA closure device, the Nitocclud PDA-R, is designed specifically for both large and medium size PDAs. The initial clinical experience with a new nitinol-based device in high altitude patients with large PDAs is described.

Chronic hypobaric hypoxia, patent arterial duct and a new interventional technique to close it.

Background: Interventional closure of patent arterial duct has become an accepted alternative to surgical closure. Clinical trial with "Nit-Occlud® PDA-R".

Methods And Results: To assess the safety and efficacy of the device, we performed a prospective clinical study between June, 2009 and December, 2010 in La Paz, Bolivia.

[Treatment of the floating shoulder. Eight cases].

Objective: To show the experience in management of eight cases of floating shoulder.

Material And Methods: Descriptive, ambispective, longitudinal and observational study of eight patients treated during the period of November 2003 to April 2005. We determined age, sex, mechanisms of injury, injuries associated to the extremity and other systems and functional results were evaluated.