The properties of functional oxide heterostructures are strongly influenced by the physics governing their interfaces. Modern deposition techniques allow us to accurately engineer interface physics through the growth of atomically precise heterostructures. This enables minute control over the electronic, magnetic, and structural characteristics, which in turn allows for the tuning of the properties of the heterostructures and can even lead to the emergence of properties not present in the individual heterostructure components.
View Article and Find Full Text PDFCharge-transfer phenomena at heterointerfaces are a promising pathway to engineer functionalities absent in bulk materials but can also lead to degraded properties in ultrathin films. Mitigating such undesired effects with an interlayer reshapes the interface architecture, restricting its operability. Therefore, developing less-invasive methods to control charge transfer will be beneficial.
View Article and Find Full Text PDFNat Genet
March 2021
Memristive devices are among the most prominent candidates for future computer memory storage and neuromorphic computing. Though promising, the major hurdle for their industrial fabrication is their device-to-device and cycle-to-cycle variability. These occur due to the random nature of nanoionic conductive filaments, whose rupture and formation govern device operation.
View Article and Find Full Text PDFTransl Psychiatry
September 2019
Schizophrenia, Schizoaffective, and Bipolar disorders share behavioral and phenomenological traits, intermediate phenotypes, and some associated genetic loci with pleiotropic effects. Volumetric abnormalities in brain structures are among the intermediate phenotypes consistently reported associated with these disorders. In order to examine the genetic underpinnings of these structural brain modifications, we performed genome-wide association analyses (GWAS) on 60 quantitative structural brain MRI phenotypes in a sample of 777 subjects (483 cases and 294 controls pooled together).
View Article and Find Full Text PDFOxide-based valence-change memristors are promising nonvolatile memories for future electronics that operate on valence-change reactions to modulate their electrical resistance. The memristance is associated with the movement of oxygen ionic carriers through oxygen vacancies at high electric field strength via structural defect modifications that are still poorly understood. This study employs a CeGdO solid solution model to probe the role of oxygen vacancies either set as "free" or as "immobile and clustered" for the resistive switching performance.
View Article and Find Full Text PDFJ Am Med Inform Assoc
May 2015
Background: As large genomics and phenotypic datasets are becoming more common, it is increasingly difficult for most researchers to access, manage, and analyze them. One possible approach is to provide the research community with several petabyte-scale cloud-based computing platforms containing these data, along with tools and resources to analyze it.
Methods: Bionimbus is an open source cloud-computing platform that is based primarily upon OpenStack, which manages on-demand virtual machines that provide the required computational resources, and GlusterFS, which is a high-performance clustered file system.