Publications by authors named "Joban Ghuman"
Background Incidental findings of coronary artery calcifications (CACs) are not consistently reported, and the clinical significance relating to cardiovascular outcomes remains to be established. In this single-center cross-sectional study, we assessed the association between incidental coronary artery calcification documented on formal chest CT reports and the incidence of major adverse cardiovascular events (MACE). Methods A MACE was defined as the occurrence of stroke or transient ischemic attack or ST-segment elevation myocardial infarction, non-ST-elevation myocardial infarction, or undergoing coronary artery bypass grafting.
View Article and Find Full Text PDFIntroduction Sodium-glucose co-transporter-2 inhibitors (SGLT2Is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) are novel antihyperglycemic agents that reduce cardiovascular mortality through insulin-independent mechanisms. In this cross-sectional study, we investigated prescription patterns of these drugs and identified inequities in antihyperglycemic utilization. Methods Unique encounters for diabetes care between January 1, 2020, and December 31, 2020, were identified through a systematic query of our healthcare system's database.
View Article and Find Full Text PDFBackground: The development of highly active anti-retroviral therapy (HAART) has markedly prolonged the life expectancy of individuals with human immunodeficiency virus (HIV). The prevalence of age-related cardiovascular disease (CVD) and arrhythmias is therefore expected to increase among the HIV-positive population.
Objectives: We aimed to assess the trends in prevalence, and inpatient outcomes among patients with HIV and atrial fibrillation (AF).
Ponatinib-associated panniculitis: Case report and review of the literature.
Cancer Treat Res Commun
December 2021
Article Synopsis
- Ponatinib is a tyrosine kinase inhibitor used to treat specific types of leukemia, including chronic myelogenous leukemia and acute lymphoblastic leukemia.
- It can have side effects such as neutropenia (low white blood cell count), arterial thrombosis (blood clots in the arteries), and hypertension (high blood pressure).
- A case study is presented involving a 49-year-old woman who developed panniculitis (inflammation of fat tissue) after a short period on ponatinib, along with a summary of other research on TKI-related panniculitis.
Association between electrocardiographic features and mortality in COVID-19 patients.
Ann Noninvasive Electrocardiol
July 2021
Article Synopsis
- Cardiovascular issues, including arrhythmias, have been linked to COVID-19, driven by systemic inflammation, but specifics regarding their types and effects on mortality need more understanding.
- A study of 186 COVID-19 patients found that conditions like atrial fibrillation and ST-segment depression were associated with higher mortality, and those who survived exhibited different ventricular rates.
- While anticoagulation therapy appeared to lower death risk, this needs further research; overall, more extended studies are needed to investigate the causes and management of these heart conditions related to COVID-19.
Drug-induced thrombocytopenia is rarely associated with statin medications. We describe the case of a 69-year-old woman who developed refractory thrombocytopenia following atorvastatin use. To our knowledge, this is the fourth reported case of atorvastatin-induced thrombocytopenia and the first reported case of atorvastatin-induced refractory thrombocytopenia.
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