Publications by authors named "Jing-Ping Cheng"

Sarcopenia is an age-related skeletal muscle disease associated with adverse outcomes such as falls, decreased function, frailty, and death, and is a significant global public health problem that impairs the functioning of individuals. Aging is intensifying, the number of people with sarcopenia is increasing, and there are currently no specific treatment drugs for sarcopenia. The clinical pathogenesis of sarcopenia is extremely complex, and the underlying mechanism of immunosenescence and dysbiosis associated with aging on sarcopenia is not well studied, and they are also potential therapeutic targets for sarcopenia.

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Rationale: Fish gallbladder poisoning is an acute poisoning caused by eating fish gallbladders, which can damage the functions of multiple organs such as the heart, liver, and kidneys, and can be fatal in severe cases.

Patient Concerns: A 56-year-old female farmer, believing in a folk remedy, consumed the gallbladder of a black carp (Mylopharyngodon piceus) weighing approximately 4 kg to treat her cough. She subsequently developed abdominal pain and diarrhea for 6 days, followed by 1 day of anuria.

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Background: Hip fractures represent a significant public health challenge among middle-aged and older adults, with substantial implications for health and quality of life. This study aimed to investigate the association between estimated pulse wave velocity (ePWV) and hip fracture risk, with a comprehensive analysis of both overall and female population cohorts.

Methods: Utilizing data from the China Health and Retirement Longitudinal Study (CHARLS), this prospective cohort study included 11,024 participants aged 45 and older, with a 9-year follow-up period (2011-2020).

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The trend of aging of the global population is becoming more and more significant, and the incidence of age-related diseases continues to rise.This phenomenon makes the problem of aging gradually attracted wide attention of the society, and gradually developed into an independent research field.As a vital defense mechanism of the human body, the immune system changes significantly during the aging process.

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Article Synopsis
  • Insulin autoimmune syndrome (IAS) is a serious condition marked by spontaneous hypoglycemia, characterized by high levels of immune-reactive insulin and insulin autoantibodies, and can occur without prior insulin treatment, leading to a new classification known as non-classical IAS.
  • A case study highlights an 83-year-old male with non-classical IAS, presenting psychiatric symptoms and Whipple's triad, indicating severe hypoglycemia while also showing elevated insulin levels despite low C-peptide levels, suggesting an autoimmune response.
  • Treatment for non-classical IAS includes stopping relevant medications, using hormones or immunosuppressants, plasma exchange, and making lifestyle changes to relieve symptoms effectively.*
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Background: Venous thromboembolism significantly contributes to patient deterioration and mortality. Management of its etiology and anticoagulation treatment is intricate, necessitating a comprehensive consideration of various factors, including the bleeding risk, dosage, specific anticoagulant medications, and duration of therapy. Herein, a case of lower extremity thrombosis with multiple primary malignant tumors and high risk of bleeding was reviewed to summarize the shortcomings of treatment and prudent anticoagulation experience.

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Article Synopsis
  • Screening suitable reference genes is crucial for accurate gene expression analysis using qRT-PCR in Aconitum vilmorinianum.
  • The study evaluated 19 candidate reference genes through expression profiling in various plant organs, identifying PP2A1 and EF1α as the most stable candidates.
  • Different analysis methods yielded varying results, but the comprehensive approach confirmed PP2A1 and EF1α as optimal reference genes for accurate expression studies.
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is a perennial plant in the Scrophulariaceae family with a high value of medicinal in Tibetan medicine. In this study, we assembled and characterized the complete chloroplast genome of as a resource for future studies on this species. The chloroplast genome was 152,789 bp in size, with a large single-copy (LSC) region of 83,642 bp, a small single-copy (SSC) region of 17,795 bp, separated by two inverted repeat (IR) regions of 25,676 bp each.

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