Validity and Reliability of the Korean Version of the Self-Care Self-Efficacy Scale for Patients With Heart Failure: A Psychometric Evaluation.

Aim: The psychometric properties of the 10-item Self-Care Self-Efficacy scale have not yet been established in the Korean language. This study aimed to evaluate its validity and reliability among Korean patients with heart failure (HF).

Methods: A total of 159 patients with HF participated (mean age: 65.

Post-transcriptional control during T4 infection.

Bacteriophage T4 has provided a model system for understanding post-transcriptional regulation in prokaryotes. This review summarizes several mechanisms of RNA processing and translational control in T4 infection, focusing on the coordinated actions of phage and host RNases. Key regulators such as RNase E, RegB, and tRNA-processing enzymes are discussed, along with the roles of RNA secondary structures and the translational repressors gp32, gp43, and RegA.

Modulation of Gut Microbiota by Cacao: Insights from an In Vitro Model.

Natural products play a pivotal role in human health by exerting bioactive effects, including the modulation of the gut microbiome. Cacao, a widely consumed natural product, is rich in polyphenols and dietary fiber, which may influence microbial composition and metabolic functions. However, its effects on the gut microbiota remain poorly understood, particularly regarding inter-individual differences.

Antagonistic effect of kanamycin on kanamycin-resistant Escherichia coli infection by BtuB-targeting bacteriophages.

In combined treatments with antibiotics and bacteriophages (phages), antibiotics have the potential to influence phage infectivity, exhibiting effects that vary from synergistic to antagonistic. Here, we investigated the effects of various classes of antibiotics on Escherichia coli infection by phages that use different receptors, including vitamin B outer membrane transporter (BtuB), lipopolysaccharide (LPS), outer membrane protein A (OmpA), and nucleoside-specific porin (Tsx). Among the antibiotics tested, ampicillin did not affect phage infection, whereas colistin, chloramphenicol, and tetracycline inhibited phage infection irrespective of the phage receptor.

Tevenvirinae phages encode a family of LSm-like fold proteins.

Uncharacterized bacteriophage proteins typically have little homology outside the phage world. An example is the T4 early protein GoF. Although the function of wild type is not known, the GoF mutant (D25Y) affects the level of T4 gene mRNA under certain conditions.

A Mediating Effect of Psychological Distress in the Relationship Between Performance Status and Health-Related Quality of Life of Patients with Female Cancer.

This study aimed to examine whether anxiety and depressive symptoms mediate the relationship between performance status and health-related quality of life (HRQL) in patients with female cancer. A poor performance status is known to adversely affect HRQL and psychological distress-particularly anxiety and depressive symptoms-which may play a key role in this relationship. Identifying the mediating role of these symptoms may offer valuable insights into the mechanisms linking the performance status and HRQL.

ClpB enhances thermotolerance in through protein disaggregation independent of DnaK.

is a leading cause of foodborne infections worldwide and primarily transmitted to humans through the consumption of contaminated poultry meat. To enhance -associated food safety, it is critical to understand how survives during the thermal processing of poultry products. In this study, we monitored the survival of 86 .

Amino acid residues in the tail fiber differentiate the host specificity of bacteriophage.

is a Gram-negative pathogen that causes severe infections such as neonatal meningitis and sepsis. Bacteriophages (phages) rely on tail fibers for host recognition and infection, but the mechanisms of how phages recognize their bacterial hosts are not completely elucidated. In this study, two lytic phages belonging to the family, CRES7 and CRES9, were isolated from sewage in South Korea.

Beliefs and attitudes of family caregivers of People with dementia toward advance care planning: A Q methodology study.

Family caregivers' perspectives for advance care planning (ACP) are critically important to reflect the end-of-life wishes of people with dementia. Culture can influence ACP practice and people's perspectives toward it. Little is known about family caregivers' perspectives toward ACP in Asian countries, especially in Korea.

Virulent Bacteriophages for Controlling Shiga Toxin-Producing Escherichia coli (STEC) Without Inducing Toxin Production.

Shiga toxin-producing Escherichia coli (STEC) infections pose a significant public health challenge, characterized by severe complications including hemolytic uremic syndrome (HUS) due to Shiga toxin (Stx) production. Current therapeutic approaches encounter a critical limitation, as conventional antibiotic treatment is contraindicated due to its propensity to trigger bacterial SOS response and subsequently enhance Stx production, which increases the likelihood of developing HUS in antibiotic-treated patients. The lack of effective, safe therapeutic options has created an urgent need for alternative treatment strategies for STEC infections.

Factors Associated With Self-management in Adults With Type 1 or Type 2 Diabetes: A Cross-sectional, Correlational Study.

Background: Poor self-management in adults with type 1 diabetes (T1DM) or type 2 diabetes (T2DM) leads to increased diabetes complications. Factors associated with self-management in T1DM and T2DM may differ due to the different methods for controlling blood glucose.

Purpose: The aim of this study was to examine the associations of modifiable physical, cognitive, and psychosocial factors and the nonmodifiable factor of age with overall self-management, diet, exercise, blood glucose testing (BGT), foot care, and smoking in adults with T1DM or T2DM.

Pleiotropic cellular responses underlying antibiotic tolerance in .

Antibiotic tolerance enables antibiotic-susceptible bacteria to withstand prolonged exposure to high concentrations of antibiotics. Although antibiotic tolerance presents a major challenge for public health, its underlying molecular mechanisms remain unclear. Previously, we have demonstrated that develops tolerance to clinically important antibiotics, including ciprofloxacin and tetracycline.

Evaluating dyadic factors associated with self-care in patients with heart failure and their family caregivers: Using an Actor-Partner Interdependence Model.

Dyadic conditions of patients with heart failure and their caregivers may affect both patient self-care and caregiver contribution to patient self-care (CCPS). The purpose of this study was to examine the relationships of patient-caregiver physical function and depressive symptoms to the patient self-care (maintenance and management) and CCPS. Data from 55 were analyzed using an Actor-Partner Interdependence Model to address the aim through AMOS.

Relationships of Multidimensional Factors to Diabetes Complications: A Cross-Sectional, Correlational Study.

Background: Diabetes complications are prevalent in people with diabetes, causing considerable individual suffering and increased health costs. However, the relationships of multidimensional, modifiable, and nonmodifiable factors to diabetes complications and the role of diabetes distress have been rarely examined.

Objective: The aims of this study were to examine the associations of age, sex, knowledge, self-efficacy, self-compassion, resilience, self-esteem, depressive symptoms, diabetes distress, social support, and body mass index with diabetes complications and to investigate the mediating role of diabetes distress.

Perspectives on advance care planning and related end-of-life care in people with heart failure: A Q methodology study.

Negative perspectives around advance care planning (ACP) prevent people with heart failure (HF) from preparing their end-of-life (EOL) effectively. A Q methodology study was conducted to identify types of ACP perspectives in Koreans with HF. The Q sample (31 statements representing ACP perspectives) was constructed through an extensive literature review and in-depth qualitative interview.

Relationships of Psychosocial Factors to Diabetes Self-efficacy: A Cross-sectional, Correlational Study.

Background: Self-care in people with diabetes is poor, which could be influenced by positive and negative psychosocial factors. Self-efficacy is an important factor affecting self-care, and depressive symptoms and diabetes distress may directly and indirectly affect self-efficacy.

Objective: The aim of this study was to examine the relationships of depressive symptoms, diabetes distress, age, sex, self-compassion, resilience, self-esteem, and social support to diabetes self-efficacy and the mediating roles of diabetes distress and depressive symptoms in the relationships among people with diabetes.

Cold tolerance in Campylobacter jejuni and its impact on food safety.

Campylobacter jejuni is a major cause of foodborne illnesses worldwide and is primarily transmitted to humans through contaminated poultry meat. To control this pathogen, it is critical to understand its cold tolerance because poultry products are usually distributed in the cold chain. However, there is limited information regarding how this thermotolerant, microaerophilic pathogen can survive in cold and aerobic environments in the poultry cold chain.

Psychometric Properties of the Advance Care Planning Engagement Survey-9 in Cardiovascular and Metabolic Diseases.

The purpose of this study was to test the reliability and validity of the Advance Care Planning Engagement Survey-9 Korean version in patients with cardiovascular diseases or metabolic syndrome. In this cross-sectional study, data on advance care planning engagement, registration of advance directives and the intention, and sociodemographic characteristics were collected from 105 patients (mean age, 66.3 years) at 4 medical institutions.

Relationships of multidimensional factors to self-management in patients with diabetes: A Cross-sectional, correlational study.

Poor self-management in patients with diabetes is a consistent issue, leading to diabetes complications. The purpose of this study was to examine the relationships of demographic, cognitive, psychological, social, and physiological factors to self-management in patients with diabetes. In this cross-sectional, correlational study, data were collected from 98 patients through REDCap in 2023.

Effects of Meditation Intervention on Self-management in Adult Patients With Type 2 Diabetes: A Systematic Literature Review and Meta-analysis.

Background: Diabetes complications are prevalent and cause adverse effects on the physical, psychological, and economic status of adult patients with type 2 diabetes. Meditation may positively affect self-management and, in turn, reduce diabetes complications. However, the systematic examination of the effects of meditation without additional components on self-management in this population have been rarely examined.

The moderating effect of attitudes in the relationship between knowledge and self-efficacy in palliative care among nurses: A cross-sectional, correlational study.

Provision of palliative care to patients with advanced chronic diseases or old populations is suboptimal, which results in unnecessary suffering of and burden to patients, caregivers, and society. Low self-efficacy in palliative care among nurses is a factor affecting suboptimal utilization of palliative care. Poor knowledge is a factor affecting low self-efficacy in palliative care of nurses.

Physical Symptoms, Depressive Symptoms, and Quality of Life in Patients With Heart Failure: Cluster Analysis.

Background: Physical and psychological symptoms are prevalent in patients with heart failure (HF) and are associated with poor quality of life (QOL) and high hospitalization rates. Thus, it is critical to identify symptom clusters to better manage patients with high-risk symptom cluster(s) and to reduce adverse effects.

Objective: The aims of this study were to identify clusters of physical HF symptoms (ie, dyspnea during daytime, dyspnea when lying down, fatigue, chest pain, edema, sleeping difficulty, and dizziness) and depressive symptoms and to examine their association with QOL in patients with HF.

Structural Relationships Between Cognitive Function, Depressive Symptoms, Self-Care Confidence, and Maintenance in Patients With Heart Failure.

Introduction: In order to promote self-care maintenance behavior in patients with heart failure (HF), it is necessary to identify the direct and indirect effects of major latent variables.

Objective: This study aimed to identify structural relationships between different domains of cognitive function, depression and self-care confidence, and self-care maintenance.

Methods: This descriptive study involved a secondary analysis using data of 201 patients with HF from two observational studies in three hospitals in Korea.

Characterization and genomic study of EJP2, a novel jumbo phage targeting antimicrobial resistant .

The emergence of antimicrobial resistance (AMR) has noticeably increased in recent years worldwide and causes serious public health concerns. As alternatives to antibiotics, bacteriophages are regarded as promising antimicrobial agents. In this study, we isolated and characterized a novel jumbo phage EJP2 that specifically targets AMR strains.