Publications by authors named "Jiang-Nan Huang"
Avian pathogen Escherichia coli (APEC) poses a significant threat to poultry farming, causing colibacillosis in various hosts, including chickens, ducks, geese, and pigeons. This study aimed to investigate the molecular epidemiology of APEC in Jiangxi Province, China, to inform prevention and control strategies. Between 2020 and 2024, 186 APEC strains were isolated and identified, with 88.
View Article and Find Full Text PDFAvian pathogenic (APEC) is an important bacterial pathogen that causes severe respiratory and systemic infections in poultry. Our previous research investigated the prevalence and antimicrobial resistance phenotypes of APEC isolated from poultry flocks in Jiangxi Province, China. The present study aims to further identify the serotypes and the carbapenem-resistant gene in APEC strains.
View Article and Find Full Text PDFPathogenicity and identification of host adaptation genes of the avian pathogenic O145 in duck.
Front Cell Infect Microbiol
November 2024
Article Synopsis
- APEC O145 is a significant bacterial pathogen impacting poultry in China, with recent studies indicating its rise as a predominant serogroup.
- A virulent strain called NC22 was analyzed to understand its pathogenic mechanisms through whole-genome sequencing and by observing its behavior in duck liver compared to lab cultures.
- The study found that NC22 infection led to severe symptoms in ducks and identified 87 differentially expressed genes related to metabolism and host adaptation, shedding light on the complex interactions between APEC O145 and its hosts.
Article Synopsis
- Poultry farming is widespread but threatened by pathogenic bacterial infections, particularly those resistant to antibiotics, highlighting a significant issue in meat production.
- A study in Jiangxi Province, China, analyzed bacterial pathogens from diseased poultry, revealing a 62.90% isolation rate with major pathogens like avian pathogenic E. coli (APEC) and Salmonella spp.
- APEC isolates exhibited high levels of antimicrobial resistance, with many resistant to multiple drug categories, indicating an urgent need for better disease management in poultry to combat emerging antimicrobial resistance (AMR).
Expression, Regulation, and Functional Characterization of FST Gene in Porcine Granulosa Cells.
Anim Biotechnol
October 2016
Proliferation, differentiation, and estrogen secretion of granulosa cells are the key factors affecting the estrous after weaning in sows. The objective of this study was to evaluate the expression of Follistatin (FST) in the ovary of Xiushui Hang and Duroc sows at weaning and estrus, the effect of FSH on transcript abundance of FST gene in granulosa cells and the role of FST gene in the weaning to estrus using siRNAs targeted to FST gene. In the present study, expression of the FST mRNA was evaluated by real time PCR.
View Article and Find Full Text PDFInositol polyphosphate-5-phosphatase F (INPP5F) is one of the largest families of phosphoinositide phosphatases, 5-phosphatase. It contains a Sac domain whose amino acids are essential for inositol polyphosphate phosphatase activities. Here, we assigned the porcine INPP5F to SSC14q29 by using SCHP and IMpRH.
View Article and Find Full Text PDFImprinted genes are expressed monoallelically depending on their parental origin, and escape the Mendel's laws of heredity. They play important roles in the mammalian development, growth, and behavior. Placenta is a key tissue for the normal development and growth of fetus.
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