Publications by authors named "Jess Blickwedel"
Background Seizure severity can change from one seizure to the next within individual people with epilepsy. It is unclear if and how seizure severity is modulated over longer timescales. Characterising seizure severity variability over time could lead to tailored treatments.
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- Researchers studied how important it is to fully remove areas of the brain that cause seizures during surgery for patients who can't control their epilepsy with medicine.
- They looked at data from 63 patients and found that most had a lot of the problem areas taken out, but it didn't seem to help them avoid seizures afterward.
- The study concluded that just removing the seizure areas isn't enough to guarantee no more seizures, suggesting that there might be other reasons for seizures after surgery.
Objective: Understanding fluctuations in seizure severity within individuals is important for determining treatment outcomes and responses to therapy, as well as assessing novel treatments for epilepsy. Current methods for grading seizure severity rely on qualitative interpretations from patients and clinicians. Quantitative measures of seizure severity would complement existing approaches to electroencephalographic (EEG) monitoring, outcome monitoring, and seizure prediction.
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