Publications by authors named "Jennifer D Claytor"
Background: Pouchitis is common among patients with ulcerative colitis (UC) who have had colectomy with ileal pouch-anal anastomosis. Antibiotics are first-line therapy for pouch inflammation, increasing the potential for gut colonization with multi-drug resistant organisms (MDRO). Fecal microbial transplant (FMT) is being studied in the treatment of pouchitis and in the eradication of MDRO.
View Article and Find Full Text PDFFecal Microbiota Transplantation (FMT) in Ulcerative Colitis: Holding Out for a Superdonor?
Clin Gastroenterol Hepatol
March 2025
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- The study discusses the risks of starting biologic therapies for rheumatologic disorders without conducting prior HIV screening, highlighting cases where patients were discovered to have undiagnosed HIV after starting treatment.* -
- Three patient cases are analyzed: a 53-year-old man with rheumatoid arthritis, a 55-year-old woman with hidradenitis suppurativa, and a 32-year-old man with inflammatory bowel disease, all of whom faced complications after beginning biologic therapy.* -
- Each case demonstrated that undiagnosed HIV infection led to unexpected health issues and complications related to their conditions, emphasizing the need for routine HIV screening before initiating immunosuppressive treatments.*
Objectives: To determine risk factors for body image dissatisfaction among pediatric patients with inflammatory bowel disease (IBD).
Study Design: We performed a cross-sectional study of children aged 9-18 years in the IBD Partners Kids & Teens cohort. Participants completed surveys including demographics, disease characteristics and activity indices, and psychosocial outcomes measured by IMPACT-III questionnaires.
Fecal microbial transplant for inflammatory bowel disease.
Curr Opin Clin Nutr Metab Care
September 2020
Purpose Of Review: The purpose of this brief review is to investigate the current utility of fecal microbial transplantation (FMT) to ameliorate dysbiosis contributing to inflammatory bowel disease pathogenesis.
Recent Findings: Increasing data from randomized, controlled trials support a role for multiple FMT administrations in the induction of remission and even as a maintenance therapy in mild-to-moderate Ulcerative Colitis. Small series and one small randomized controlled trial among patients with Crohn's Disease and with pouchitis continue to produce conflicting clinical results and microbial profile data on the host and donor levels.
Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) represents a spectrum of rare but severe mucocutaneous drug reactions. Gastrointestinal involvement of SJS/TEN is associated with high morbidity and mortality and often presents 2-3 weeks after the initial appearance of skin lesions. There are no evidence-based treatment algorithms for the management of SJS/TEN.
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