Publications by authors named "Javad Hosseini Nejad"

Ocular tuberculosis (OTB) is a chronic eye infection caused by . Some cases of myelitis are associated with (EBV), with 1-5% of EBV infections leading to neurologic complications. We describe a 34-year-old Iranian woman with OTB and EBV coinfection.

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Article Synopsis
  • - This study investigates the relationship between specific gene polymorphisms of neprilysin (NEP) and the risk of Alzheimer’s disease (AD) in an Iranian population, focusing on two single nucleotide polymorphisms (SNPs), rs6797911 and rs3736187.
  • - The research involved comparing 120 diagnosed AD patients with 120 healthy individuals, ensuring that both groups were matched for key demographic characteristics, with genotyping conducted via the ARMS-PCR technique.
  • - Results revealed a significant association between both SNPs and increased AD risk, especially rs3736187, which indicated a strong link under a log-additive model, suggesting that genetic variations in the NEP gene may influence Alzheimer’s susceptibility in
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Article Synopsis
  • Alzheimer's disease (AD) is a neurodegenerative disorder that leads to memory loss and cognitive decline, often with mood changes and confusion, and the search for its causes is focused on the cerebral cortex through analysis of gene expression.
  • A study analyzed RNA expression in the frontal, temporal, and entorhinal cortex of AD patients and found key genes showing significant changes, particularly AEBP1 and COLEC12, which were also assessed in peripheral blood samples of late-onset AD patients.
  • The research connects the up-regulation of AEBP1 and COLEC12 to the TGF-β signaling pathway and suggests these genes could serve as important diagnostic markers for differentiating late-onset AD patients from healthy
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Encephalitis occasionally occurs due to the central nervous system (CNS) infection by Varicella-zoster virus (VZV). The coincidence of herpes Encephalitis-brain infection and brucellosis occurs rarely. In this case, a 56-year-old woman was described with low consciousness, seizures, fever, and mood disorders.

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Background: The involvement of the central nervous system is a frequent yet underestimated complication of diabetes mellitus. Visual evoked potentials (VEP) are a simple, sensitive, and noninvasive method for detecting early alterations in central optic pathways. The objective of this paralleled randomized controlled trial was to evaluate the impact of ozone therapy on visual pathways in diabetic patients.

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The COVID-19 mainly causes respiratory disorders with high infection and severe morbidity and mortality. Neurologists have concerns about potential neurological side effects, profits, and timing of COVID-19 vaccines. This study aimed to review systematically research for the COVID-19 vaccine and neurological complications.

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Background: Coronavirus disease 2019 (COVID-19), a global issue now, can have a variety of clinical manifestations. Hundreds of articles have discussed different aspects of this infectious disease, such as physiopathology, epidemiology, clinical manifestations and treatment protocols. Recently, neurological manifestations of the disease have been found to be pretty common among COVID-19 patients.

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Acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is spreading around the world. Patients with coronavirus disease 2019 (COVID-19) typically present fever, cough, and respiratory illnesses. It has been revealed that the comorbidities can turn it into severe types, and the managements meet unpredicted complications.

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COVID-19 encephalitis is a rare condition usually presenting with altered mental status. Simultaneous presence of anti-NMDAR antibody and SARS-CoV-2 virus in CSF is a very rare condition described in a few case reports so far. On the other hand, brain edema is an unusual presentation of anti-NMDAR encephalitis.

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents respiratory symptoms as the most common clinical manifestations. Similar to some other viral infections, it can cause severe neurological damages. Here, we describe a 40-year-old man case who initially was admitted to a major hospital with presenting 7 days with weak flu-like symptoms (cough) and fever then presented neurology signs for 3 days.

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