Background: We aimed to describe the prevalence of exposure to traumatic events and post-traumatic stress disorder (PTSD) in pregnant women attending antenatal care (ANC) in rural Ethiopia. We hypothesised that antenatal PTSD symptoms would be associated with previous obstetric complications and intimate partner violence (IPV) and impact negatively on women´s satisfaction with ANC.
Methods: The design was a facility-based cross-sectional study in primary health centres providing ANC in southern Ethiopia.
Commun Med (Lond)
August 2025
Background: In 2017 NHS England started rolling out a model where women have continuity of carer with the same midwifery team throughout the perinatal period. This study uses national data to test whether women of different groups receiving midwife continuity of carer had lower stillbirth rates and higher rates of a first feed of breast milk than women receiving standard care.
Methods: We compared the two outcomes for women placed on the midwife continuity of carer pathway by 24 weeks and women receiving standard care in England, with logistic regression standardising between groups.
Objectives: To investigate maternal mortality in the context of children's social care (CSC) involvement, and to explore the quality of maternity care that women with CSC involvement received.
Design: National cohort study and confidential enquiry.
Setting: MBRRACE-UK (Mothers and Babies: Reducing Risk through Audits and Confidential Enquiries across the UK) national surveillance dataset for deaths that occurred during pregnancy or up to a year after pregnancy, UK, 2014-22.
Progress: The past ten years have seen uneven developments in women's and adolescents' health and reproductive rights. Globally, reductions of maternal and neonatal mortality rates and adolescent birth rates have been achieved along with improvements in coverage of key reproductive and maternal health services. However, preterm birth rates have not changed significantly.
View Article and Find Full Text PDFBackground: Sierra Leone has very high maternal and neonatal mortality rates, and a large proportion of these deaths occur in adolescents, a particularly vulnerable group, and is usually driven by poverty, lack of education, and sparse employment opportunities. We evaluated the feasibility and potential effects of a community-based mentoring intervention from pregnancy up to 1 year after birth to inform a subsequent larger trial aiming to reduce mortality among adolescent girls and their newborns (2YoungLives).
Methods: We conducted a parallel-arm, pilot, hybrid implementation-effectiveness cluster randomised controlled trial of the introduction of the 2YoungLives intervention as an adjunct to maternity care in rural and urban communities served by 12 peripheral health units in five districts of Sierra Leone.
Objective: To explore the role of shared decision-making (SDM) in the implementation of evidence-based practice in women with chronic hypertension planning birth and investigate the barriers and the facilitators in the provision of antenatal care.
Methods: A multimethod multisite approach was used including case-note review (n=55) and structured observations (n=18) to assess the provision of third trimester antenatal care. The barriers and facilitators to implementation were identified from semistructured qualitative interviews with healthcare professionals (n=13) and pregnant women (n=14) using inductive thematic analysis.
Objective: To examine the variation in stillbirth rates between different ethnic and socioeconomic groups within each organisational hospital group (health trust).
Design: National registry study.
Setting: All health trusts (HT) in National Health Service England.
BMC Pregnancy Childbirth
January 2025
Background: Person-centred maternal care is associated with positive experiences in high-income countries. Little is known about the transferability of this concept to non-Western, low-income settings. We aimed to explore women's experiences of care and investigate satisfaction with antenatal care (ANC) in relation to person-centred care and unmet psychosocial needs in rural Ethiopia.
View Article and Find Full Text PDFPre-eclampsia is a leading cause of maternal and neonatal mortality; 30,000 pre-eclampsia-related maternal deaths occur annually, with 70% in Sub-Saharan Africa (SSA) and 16% in South Asia. We have shown that early, accurate detection of hypertension combined with planned early delivery in women with late preterm pre-eclampsia significantly reduces stillbirth and severe maternal hypertension. We describe co-development and delivery of policy labs, working with The Policy Institute (King's College London), and local stakeholders in Sierra Leone and Zambia, to expedite integration of new knowledge into pre-eclampsia care pathways, to improve care for women and babies with the worst outcomes.
View Article and Find Full Text PDFBMC Pregnancy Childbirth
November 2024
Objective: To identify whether maternal and pregnancy characteristics associated with stillbirth differ between preterm and term stillbirth.
Design: Secondary cohort analysis of the DESiGN RCT.
Setting: Thirteen UK maternity units.
Health Soc Care Deliv Res
August 2024
BMJ Open
August 2024
Introduction: Selective fetal growth restriction (sFGR) in monochorionic twin pregnancy, defined as an estimated fetal weight (EFW) of one twin <10th centile and EFW discordance ≥25%, is associated with stillbirth and neurodisability for both twins. The condition poses unique management difficulties: on the one hand, continuation of the pregnancy carries a risk of death of the smaller twin, with a high risk of co-twin demise (40%) or co-twin neurological sequelae (30%). On the other, early delivery to prevent the death of the smaller twin may expose the larger twin to prematurity, with the associated risks of long-term physical, emotional and financial costs from neurodisability, such as cerebral palsy.
View Article and Find Full Text PDFBackground: Women who suffer an early pregnancy loss require specific clinical care, aftercare, and ongoing support. In the UK, the clinical management of early pregnancy complications, including loss is provided mainly through specialist Early Pregnancy Assessment Units. The COVID-19 pandemic fundamentally changed the way in which maternity and gynaecological care was delivered, as health systems moved to rapidly reconfigure and re-organise services, aiming to reduce the risk and spread of SARS-CoV-2 infection.
View Article and Find Full Text PDFBackground: More women are experiencing pregnancy with two or more long-term health conditions such as hypertension, depression or HIV (MLTC). Care can be complex and include multiple teams, health professionals and services. The type and range of maternity care models for these women and the role of the midwife within such models is unknown.
View Article and Find Full Text PDFPLoS One
September 2024
Background: The perinatal period is known as time of transition and anticipation. For women with social risk factors, child protection services may become involved during the perinatal period and this might complicate their interactions with healthcare providers.
Aim: To systematically review and synthesise the existing qualitative evidence of healthcare experiences of women and healthcare professionals during the perinatal period while facing child protection involvement.
Objective: To identify current practices in the management of selective fetal growth restriction (sFGR) in monochorionic diamniotic (MCDA) twin pregnancies.
Design: Cross-sectional survey.
Setting: International.
Background: Evidence suggests that obstetric violence has been prevalent globally and is finally getting some attention through research. This human rights violation takes several forms and is best understood through the narratives of embodied experiences of disrespect and abuse from women and other people who give birth, which is of utmost importance to make efforts in implementing respectful maternity care for a positive birthing experience. This study focused on the drivers of obstetric violence during labor and birth in Bihar, India.
View Article and Find Full Text PDFImplement Sci Commun
May 2024
Background: In the UK, 7.6% of babies are born preterm, which the Department of Health aims to decrease to 6% by 2025. To advance this, NHS England released Saving Babies Lives Care Bundle Version 2 Element 5, recommending the Preterm Birth Pathway for women at risk of preterm birth.
View Article and Find Full Text PDFCochrane Database Syst Rev
April 2024
Background: Midwives are primary providers of care for childbearing women globally and there is a need to establish whether there are differences in effectiveness between midwife continuity of care models and other models of care. This is an update of a review published in 2016.
Objectives: To compare the effects of midwife continuity of care models with other models of care for childbearing women and their infants.
Objective: Providing comprehensible information is essential to the process of valid informed consent. Recruitment materials designed by sponsoring institutions in English-speaking, high-income countries are commonly translated for use in global health studies in other countries; however, key concepts are often missed, misunderstood or 'lost in translation'. The aim of this study was to explore the language barriers to informed consent, focusing on the challenges of translating recruitment materials for maternal health studies into Zambian languages.
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