Publications by authors named "Jan Henje Doering"
Article Synopsis
- * A majority of participants exhibit neurodevelopmental issues (95%) and seizures (89%), with common seizure types and early onset, underscoring the severity of STXBP1-related conditions.
- * Despite identifying frequent genetic variants, no specific associations were found between these variants and particular clinical syndromes, indicating a high level of variability in the clinical presentation of STXBP1-related disorders.
Objective: Our prospective study aimed at exploring attention and executive functions in children with new-onset epilepsy prior to and during the early course of antiepileptic treatment. Sociodemographic and epilepsy-related factors were analyzed as potential predictors both of impaired cognitive functions as well as for changes in cognitive functioning in the early course of illness.
Methods: From a total group of 115 children aged six to 17years without major disabilities, 76 children were assessed longitudinally with a screening tool for attention and executive functions (EpiTrack Junior®).