Path integration impairments reveal early cognitive changes in subjective cognitive decline.

Path integration, the ability to track one's position using self-motion cues, is critically dependent on the grid cell network in the entorhinal cortex, a region vulnerable to early Alzheimer's disease pathology. In this study, we examined path integration performance in individuals with subjective cognitive decline (SCD), a group at increased risk for Alzheimer's disease, and healthy controls using an immersive virtual reality task. We developed a Bayesian computational model to decompose path integration errors into distinct components.

Path integration impairments reveal early cognitive changes in Subjective Cognitive Decline.

Path integration, the ability to track one's position using self-motion cues, is critically dependent on the grid cell network in the entorhinal cortex, a region vulnerable to early Alzheimer's disease pathology. In this study, we examined path integration performance in individuals with subjective cognitive decline (SCD), a group at increased risk for Alzheimer's disease, and healthy controls using an immersive virtual reality task. We developed a Bayesian computational model to decompose path integration errors into distinct components.

How subcultures emerge.

Sympatric speciation is typically presented as a rare phenomenon, but urban subcultures frequently emerge even in the absence of geographic isolation. Is there perhaps something that culture has but biological inheritance does not that would account for this difference? We present a novel model that combines assortative interaction and multidimensional inheritance. Our computer simulations show that assortment alone can lead to the formation of cohesive clusters of individuals with low within-group and large between-group variability even in the absence of a spatial separation or disruptive natural selection.