Publications by authors named "Jacopo Conforti"
ProMisE (Proactive Molecular Risk Classifier for Endometrial Cancer) has brought about the publication of the FIGO 2023 staging system with a significant impact in practice for endometrial cancer (EC). In this comparative study, we investigated the need for adjuvant treatment according to FIGO 2023, for each FIGO 2009 stage. We prospectively enrolled EC patients from June 2021 to June 2024, collected classical risk factors and classified according to FIGO 2009.
View Article and Find Full Text PDFCold Knife Versus Carbon Dioxide for the Treatment of Preinvasive Cervical Lesion.
Medicina (Kaunas)
June 2024
Article Synopsis
- Cervical cancer poses a major health risk for younger women, and tools like cold knife (CK) and carbon dioxide (CO) laser conization are used to treat pre-invasive lesions with the intent to cure incidental cervical cancer cases.
- A study involving 1,270 women showed that CO laser conization had a significantly lower rate of positive margins compared to CK conization (4.3% vs. 13.3%).
- Both techniques demonstrated similar oncological safety in cases of incidental cervical cancer diagnosis, with no recurrences noted after an average follow-up period of 53 months, and CO laser conization generally proved more effective at achieving clean margins.
Background: Almost 10% of women in reproductive age are diagnosed with ovarian endometriomas and can experience symptoms and infertility disorders. Ovarian endometriomas can be treated with medical or surgical therapy.
Objective: To assess whether long-term therapy with dienogest or oral cyclic estrogen-progestogens is effective in reducing the size of ovarian endometriomas, alleviating associated symptoms, and reducing the requirement for surgery.
Article Synopsis
- Grotta dei Moscerini, excavated in 1949, is a significant Neandertal site in Italy featuring 171 retouched shell tools across 21 layers, compared to 126 at Grotta del Cavallo.
- Research reveals that Neandertals not only collected shells from dead mollusks but also actively fished live clams from the sea floor, highlighting their hunting skills.
- Evidence from various archaeological sites indicates that Neandertals routinely engaged in fishing and the collection of pumice stones, showcasing their complex behaviors prior to the arrival of modern humans in Western Europe.
Having thrived in Eurasia for 350,000 years Neandertals disappeared from the record around 40,000-37,000 years ago, after modern humans entered Europe. It was a complex process of population interactions that included cultural exchanges and admixture between Neandertals and dispersing groups of modern humans. In Europe Neandertals are always associated with the Mousterian while the Aurignacian is associated with modern humans only.
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