Publications by authors named "Jacoby Clark"

Climate change continues to alter the behavior and distribution of species worldwide, with major ramifications for the transmission and risk of infectious diseases, including those caused by zoonotic vector-borne pathogens. This study explores the potential implications of climate change for one such pathogen, (the causative agent of human Lyme disease), in ticks of the far-western United States. Nymphal tick infection prevalence and density are compared against several metrics for climate, while also accounting for habitat fragmentation, mammalian species richness, and rodent tick burden to eliminate confounding variables.

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Habitat loss and forest fragmentation are often linked to increased pathogen transmission, but the extent to which habitat isolation and landscape connectivity affect disease dynamics through movement of disease vectors and reservoir hosts has not been well examined. Tick-borne diseases are the most prevalent vector-borne diseases in the United States and on the West Coast, is one of the most epidemiologically important vectors. We investigated the impacts of habitat fragmentation on pathogens transmitted by and sought to disentangle the effects of wildlife communities and landscape metrics predictive of pathogen diversity, prevalence and distribution.

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Article Synopsis
  • Ixodes scapularis and Ixodes pacificus ticks are known vectors for various pathogens, but their potential role in transmitting Bartonella spp. has been questioned, with previous studies showing these ticks lacked Bartonella spp.
  • A recent study tested 792 I. scapularis, 45 I. pacificus, and 16 I. angustus ticks from rodents in Minnesota and Washington for Bartonella using advanced PCR techniques, while also examining rodents and fleas from the same areas.
  • Results showed high prevalence of Bartonella spp. in rodents (25.6% to 27.9%) and fleas (36.8% to 45.2%), but only one larval I. scapularis tick tested
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