A Study on the Candidate Gene Association and Interaction with Measures of UV Exposure in Pseudoexfoliation Patients from India.

Purpose: Environmental and genetic factors are associated with development of Pseudoexfoliation syndrome (XFS). Here we intended to elucidate the association of candidate genes in relevance to UV exposure in these patients.

Methods: This is a case-control study of 309 subjects ( = 219 controls and 90 XFS cases) from India.

Evaluating the impact of ocular UV exposure for the development for pseudoexfoliation syndrome in a South Indian population.

Clinical Relevance: Pathophysiology of pseudoexfoliation syndrome (XFS) can be influenced by environmental factors such as solar exposure/occupational factors and genetic factors.

Background: The study aims to assess the association of lifetime ocular UV exposure and its impact on the risk of development of XFS.

Methods: All eligible subjects underwent a comprehensive ocular examination.