Publications by authors named "Isabelle Watanabe Daniel"
The association of ABC proteins with multidrug resistance in cancer.
Andrezza Viviany Lourenço Marques
,
Bruna Estelita Ruginsk
,
Larissa de Oliveira Prado
,
Diogo Eugênio de Lima
,
Isabelle Watanabe Daniel
Biochim Biophys Acta Mol Cell Res
February 2025
Article Synopsis
- Multidrug resistance (MDR) in cancer treatment, particularly for metastatic disease, is largely driven by the overexpression of ATP-binding cassette (ABC) proteins.
- A total of 20 ABC proteins were identified as associated with MDR, highlighting the importance of drug transport and sequestration within cells.
- The study emphasizes the need for further research to understand MDR mechanisms better and improve pharmacological approaches for more effective cancer treatments.