Publications by authors named "Iris L Mimpen"
Article Synopsis
- Microbial communities in the human body play a crucial role in regulating the immune system and responses to cancer treatments, with complex communities found within primary tumors.
- A comprehensive study involving 4,160 metastatic tumor biopsies revealed specific microbial patterns in different organs, higher levels of anaerobic bacteria in low-oxygen tumors, and links between microbial diversity and immune cell activity.
- The research also highlighted the role of certain bacteria, like Fusobacterium, in cancer resistance and showed how microbial communities change over time with treatment, creating valuable data for improving cancer treatment approaches.
In recent years, major advances have been made in cancer immunotherapy. This has led to significant improvement in prognosis of cancer patients, especially in the hematological setting. Nonetheless, translation of these successes to solid tumors was found difficult.
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