Publications by authors named "Inbar Linenberg"
Article Synopsis
- Large variability exists in how people respond to foods, prompting a study comparing a personalized dietary program (PDP) to standard dietary advice on health outcomes.
- The PDP tailored food choices based on individual health data, while the control group received general dietary guidelines.
- Results showed the PDP led to significant reductions in triglycerides and improvements in various secondary health markers, with no serious adverse events reported, suggesting personalized diets may benefit cardiometabolic health.
Background: Postprandial metabolomic profiles and their inter-individual variability are not well characterised. Here, we describe postprandial metabolite changes, their correlations with fasting values and their inter- and intra-individual variability, following a standardised meal in the ZOE PREDICT 1 cohort.
Methods: In the ZOE PREDICT 1 study ( = 1002 (NCT03479866)), 250 metabolites, mainly lipids, were measured by a Nightingale NMR panel in fasting and postprandial (4 and 6 h after a 3.
Background: The menopause transition is associated with unfavourable alterations in health. However, postprandial metabolic changes and their mediating factors are poorly understood.
Methods: The PREDICT 1 UK cohort (n=1002; pre- n=366, peri- n=55, and post-menopausal females n=206) assessed phenotypic characteristics, anthropometric, diet and gut microbiome data, and fasting and postprandial (0-6 h) cardiometabolic blood measurements, including continuous glucose monitoring (CGM) data.
Article Synopsis
- Continuous glucose monitors (CGMs) show potential for personalized nutrition, but their reliability for measuring glycemic responses to foods is under scrutiny.
- In a study with 394 participants, two CGM devices were worn simultaneously to assess their agreement in measuring post-meal blood glucose levels, revealing strong concordance, particularly within the same brand.
- Results indicated low variability in glucose measurements between paired devices, suggesting that CGMs can effectively characterize individual glycemic responses, supporting their use in personalized dietary recommendations.
Understanding how to modulate appetite in humans is key to developing successful weight loss interventions. Here, we showed that postprandial glucose dips 2-3 h after a meal are a better predictor of postprandial self-reported hunger and subsequent energy intake than peak glucose at 0-2 h and glucose incremental area under the blood glucose curve at 0-2 h. We explore the links among postprandial glucose, appetite and subsequent energy intake in 1,070 participants from a UK exploratory and US validation cohort, who consumed 8,624 standardized meals followed by 71,715 ad libitum meals, using continuous glucose monitors to record postprandial glycaemia.
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View Article and Find Full Text PDFMetabolic responses to food influence risk of cardiometabolic disease, but large-scale high-resolution studies are lacking. We recruited n = 1,002 twins and unrelated healthy adults in the United Kingdom to the PREDICT 1 study and assessed postprandial metabolic responses in a clinical setting and at home. We observed large inter-individual variability (as measured by the population coefficient of variation (s.
View Article and Find Full Text PDFThe larval stages of malaria vector mosquitoes develop in water pools, feeding mostly on microorganisms and environmental detritus. Richness in the nutrient supply to larvae influences the development and metabolism of larvae and adults. Here, we investigated the effects of larval diet on the development, microbiota content and permissiveness to Plasmodium of Anopheles coluzzii.
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