Synergistic effects of modified zinc oxide nanoparticle in a hybrid chitosan-gelatin hydrogel for bone regeneration.

The development of composite hydrogels with enhanced biocompatibility and osteoconductivity remains a critical focus in bone tissue engineering. In this study, we designed a double-network hydrogel composed of chitosan, and gelatin (CG), crosslinked to improve its mechanical properties for bone regeneration applications. To further enhance its bioactivity, zinc oxide nanoparticles (ZnO) were incorporated into the hydrogel matrix.

Biomechanical evaluation of composite reduction plates with variable positioning using the Henry and Thompson approaches for transverse radial fracture surgery.

Background: Radius fractures are challenging to stabilize due to complex muscle-loading conditions, requiring optimized plate positioning and material selection for effective treatment. This study addresses the biomechanical impact of plate positions (anterior, posterior, lateral) and materials in transverse radial fractures.

Hypothesis: Plate positioning and material selection significantly influence stress distribution and displacement, with lateral positioning and WE43 alloy offering biomechanical advantages.

Magnetically responsive micro-clustered calcium phosphate-reinforced cell-laden microbead sodium alginate hydrogel for accelerated osteogenic tissue regeneration.

The rising prevalence of bone injuries has increased the demand for minimally invasive treatments. Microbead hydrogels, renowned for cell encapsulation, provide a versatile substrate for bone tissue regeneration. They deliver bioactive agents, support cell growth, and promote osteogenesis, aiding bone repair and regeneration.

Nanoscale Polishing Technique of Biomedical Grade NiTi Wire by Advanced MAF Process: Relationship between Surface Roughness and Bacterial Adhesion.

Nitinol (NiTi), an alloy of nickel and titanium, wires are an important biomedical material that has been used in catheter tubes, guidewires, stents, and other surgical instruments. As such wires are temporarily or permanently inserted inside the human body, their surfaces need to be smoothed and cleaned in order to prevent wear, friction, and adhesion of bacteria. In this study, NiTi wire samples of micro-scale diameters (i.

Polyvinylidene fluoride/silk fibroin-based bio-piezoelectric nanofibrous scaffolds for biomedical application.

Since the discovery that applying electrical stimulation can promote cell growth, proliferation, and tissue regeneration, research on bio-piezoelectric materials is being actively conducted. In this study, a composite material was prepared by mixing polyvinylidene fluoride (PVDF), a conventional piezoelectric polymer, and silk fibroin (SF), a natural piezoelectric material that recently attracting attention. These two polymers were fabricated into a composite fiber mat using electrospinning technology.