The impact of sarcopenia on adverse effects and survival in patients with metastatic hormone receptor-positive breast cancer treated with CDK4/6 inhibitors.

Breast cancer is the most commonly diagnosed malignancy worldwide. In hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer (mBC), cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) are the standard treatment. Sarcopenia, characterized by progressive muscle loss, is increasingly recognized as a factor influencing cancer outcomes.

Samatya Ratio: A Novel Prognostic Indicator for Rectal Cancer.

Objective: To evaluate the prognostic potential of a new parameter, the Samatya ratio, calculated by dividing tumour volume by the albumin-derived neutrophil-to-lymphocyte ratio (Alb-dNLR), in rectal cancer patients.

Study Design: Descriptive study. Place and Duration of the Study: Department of General Surgery, Istanbul Education and Research Hospital, Istanbul, Turkiye, from January 2019 to October 2023.

A Surgical Priority for Echinococcal Cysts in the Lung and Liver: One or Two-Stage?

Aim: This study aimed to evaluate the surgical outcomes of liver and lung hydatid cysts treated either simultaneously or in separate stages. The main focus was to determine the impact of surgical timing on postoperative complications and overall patient recovery, with an emphasis on minimally invasive techniques.

Methods: A retrospective analysis was conducted on 42 patients diagnosed with concomitant liver and lung hydatid cysts between March 2009 and July 2020.

Use of Pancreatic Density on Computed Tomography to Predict Postendoscopic Retrograde Cholangiopancreatography Pancreatitis.

Introduction: Postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is a frequent complication, and its pathogenesis remains unclear, with various patient and procedural factors proposed as potential contributors. This study aimed to assess the predictive value of pancreatic to splenic density ratio on computed tomography (CT) for PEP in patients with inadvertent pancreatic duct cannulation.

Methods: This retrospective study involved 2556 patients undergoing ERCP from January 2014 to December 2020.

Lefort 1 Osteotomy Study of Maxillary Bone in Caprine Skull Model: Comparison of Different Osteotomy Techniques (Piezo Versus Lindemann Bur Versus Manual Chisel).

Objective: In this study, we aimed to compare the efficiency of different osteotomy techniques for Lefort 1 osteotomy in an experimental caprine skull model.

Methods: Twelve caprine skulls were used for the study. Skulls were divided into 3 groups: (1) manual chisel group, (2) Lindemann bur group, and (3) piezo osteotomy group.

Two Rare Benign Lesions on F-FDG PET/CT: Peliosis Hepatis and SANT.

Peliosis hepatis (PH) and sclerosing angiomatoid nodular transformation of the spleen are uncommon benign lesions. Diagnosis can be difficult in some patients. Herein, we present the case of a 28-year-old woman referred with abdominal pain who had spleen lesions.

Relationship Between Sclerostin Levels and Coronary Artery Calcification and Plaque Composition.

Objective: The primary function of sclerostin is the regulation of bone metabolism. Research investigating the cardiovascular effects of sclerostin had conflicting results. We aimed to study serum sclerostin levels in coronary artery plaque types.

The Impact of Isotretinoin Therapy on the Nasal Skin Thickness and Elasticity: An Ultrasonography and Elastography Based Assessment in Relation to Dose and Duration of Therapy.

Background: This study aimed to evaluate the impact of isotretinoin therapy on the nasal skin thickness and elasticity with regard to implications for rhinoplasty METHODS: A total of 40 acne vulgaris patients (mean±SD age: 20.9 ± 3.0 years, 65.

Assessment of epicardial adipose tissue thickness and total calcium score in sarcoidosis patients.

Objective: Increased thickness of epicardial adipose tissue (EAT) and the total coronary artery calcium score (TCACS) are independent predictors of atherosclerosis. The aim of this study was to investigate whether EAT thickness, measured using thoracic computed tomography, and TCACS were greater in patients with sarcoidosis.

Methods: This was a retrospective study.

Peripheral Facial Nerve Palsy After Ventriculoperitoneal Shunt Surgery: An Anatomical Perspective.

In this report, we present a case of peripheral facial nerve palsy (FNP) due to injury of the facial nerve trunk that occurred during tunneling of a VP shunt catheter. We aimed to present the preventive measures by taking the anatomical causes of this complication. A 75-year old was stated a VP shunt surgery for treatment of Normal Pressure Hydrocephalus (NPH).

Comparison of piezosurgery, percutaneous osteotomy, and endonasal continuous osteotomy techniques with a caprine skull model.

Background: Osteotomy is a crucial step in rhinoplasty, which can have a significant impact on the outcome. In addition to previous percutaneous (external perforating) and endonasal (internal) approaches, piezosurgery has been used in rhinoplasty practice since 2007. This experimental model was planned to compare the three osteotomy techniques.