Publications by authors named "Hussein N Ghanem"
Article Synopsis
- Novel univariate and chemometrics-aided UV spectrophotometric methods were developed to accurately estimate a mixture of olanzapine, fluoxetine HCL, and its impurity without prior separation, achieving high accuracy (98-102%) and precision (<2%).
- The study employed advanced techniques like Partial Least Squares (PLS) and Artificial Neural Networks (ANNs) that improved model reliability using Latin hypercube sampling, resulting in lower limits of quantification (LOQs) and minimal prediction errors for all substances.
- The methods demonstrated a significant eco-friendly approach, scoring high in environmental assessments (NEMI, GAPI, and RGB 12), indicating effective compliance with green analytical chemistry principles.
