Publications by authors named "Huige Zhai"
Multimodal data fusion reveals functional and neurochemical correlates of Parkinson's disease.
Neurobiol Dis
July 2024
Background: Neurotransmitter deficits and spatial associations among neurotransmitter distribution, brain activity, and clinical features in Parkinson's disease (PD) remain unclear. Better understanding of neurotransmitter impairments in PD may provide potential therapeutic targets. Therefore, we aimed to investigate the spatial relationship between PD-related patterns and neurotransmitter deficits.
View Article and Find Full Text PDFAlteration of intracerebral metabolites and subjective sleepiness by acute caffeine administration in adults.
Quant Imaging Med Surg
December 2023
Article Synopsis
- * Methodology: Researchers used advanced imaging techniques on 45 healthy adults, excluding those with neurological disorders or certain substance habits, to measure changes in brain metabolites before and after caffeine intake, alongside subjective sleepiness assessments.
- * Findings indicate significant variations: The study found notable changes in key metabolites, especially among those who consumed more caffeine, with reductions in certain metabolites like GABA and increases in others such as GPC, demonstrating how caffeine can influence brain
Clinical Breast MRI-based Radiomics for Distinguishing Benign and Malignant Lesions: An Analysis of Sequences and Enhanced Phases.
J Magn Reson Imaging
September 2024
Article Synopsis
- Previous studies on breast lesion calcification have shown varying results due to different imaging techniques and enhancement phases, with uncertainty about the best approach.
- The study aimed to find the most effective MRI radiomics model for identifying breast lesions and evaluate its usefulness for guiding biopsies using multiparametric MRI.
- Results revealed that the best performing radiomics model combined contrast-enhanced MRI with diffusion-weighted and T2-weighted imaging, achieving a high accuracy and significantly improved specificity for diagnosis compared to traditional methods.*
Introduction: Despite verifying proton magnetic resonance spectroscopy (H-MRS) for focal localization in magnetic resonance imaging (MRI)-negative temporal lobe epilepsy (TLE), it is necessary to illustrate metabolic changes and screen for effective biomarkers for monitoring therapeutic effect. We used H-MRS to investigate the role of metabolic levels in MRI-negative TLE.
Materials And Methods: Thirty-seven patients ( = 37, 14 women) and 20 healthy controls ( = 20, 11 women) were investigated by H-MRS.
Background: 125I BT is an effective radiotherapy for prostate cancer. However, comparison data of GI and GU toxicities between BT, BT + EBRT, and EBRT-alone patient groups is limited.
Objective: To define the GI and GU toxicities in prostate cancer to prevent adverse events after treatment.