Successful Surgical Management of Giant Cardiomegaly in a Patient With Multivalvular Heart Disease: A Case Report and Literature Review.

Cardiomegaly, particularly in its extreme form, is a rare but clinically significant manifestation of chronic valvular heart disease. While a cardiothoracic ratio (CTR) greater than 0.50 indicates cardiac enlargement, a CTR exceeding 0.

Optimizing treatment of the novel intra-oral negative pressure for obstructive sleep apnea.

Study Objectives: Intra-oral negative pressure therapy (OPT) for obstructive apnea delivers a negative pressure into the oral cavity to increase the upper airway patency and has been shown as an effective CPAP alternative treatment. Rather than one-size-fits-all pressure, it is believed that individualized titration of the negative pressure is needed to achieve the optimal treatment effectiveness. This study aims to evaluate the outcome of OPT after the pressure titration process.

Lemierre's Syndrome Caused by Klebsiella pneumoniae: A Case Report and Literature Review.

Lemierre's syndrome is a rare condition that involves anaerobic sepsis following pharyngitis and is characterized by a high mortality rate. It often manifests as a septic embolism within the internal jugular vein due to oropharyngeal infections, leading to vein wall inflammation. Despite modern antibiotics, Lemierre's syndrome remains underdiagnosed and poses a significant threat.

[Effects of white organic light-emitting devices using color conversion films on electroluminescence spectra].

The authors report a novel white organic light-emitting device (WOLED), which uses a strategy of exciting organic/ inorganic color conversion film with a blue organic light-emitting diode (OLED). The luminescent layer of the blue OLED was prepared by use of CBP host blended with a blue highly fluorescent dye N-BDAVBi. The organic/inorganic color conversion film was prepared by dispersing a mixture of red pigment VQ-D25 and YAG : Ce3+ phosphor in PMMA.

Subunit assembly of N-methyl-d-aspartate receptors analyzed by fluorescence resonance energy transfer.

N-methyl-d-aspartate (NMDA) receptors play major roles in synaptic transmission and plasticity, as well as excitotoxicity. NMDA receptors are thought to be tetrameric complexes mainly composed of NMDA receptor (NR)1 and NR2 subunits. The NR1 subunits are required for the formation of functional NMDA receptor channels, whereas the NR2 subunits modify channel properties.