Association between inflammatory burden index and risk of heart failure: evidence from NHANES 2003-2017.

Background: Systemic inflammation contributes to the progression of heart failure (HF). This study aims to investigate the association between inflammatory burden index (IBI) and HF risk.

Methods: In this cross-sectional study of NHANES 2003-2017, data from 19,856 participants were analyzed, including 652 participants with HF and 19,204 without HF.

Tanshinone IIA derivatives induced S-phase arrest through stabilizing c-myc G-quadruplex DNA to regulate ROS-mediated PI3K/Akt/mTOR pathway.

Herein, a derivate from tanshinone IIA, 1,6,6-trimethyl-11-phenyl-7,8,9,10-tetrahydro-6H-furo[2',3':1,2]phenanthro[3,4-d]imidazole (TA25), has been synthesized and investigated as potential inhibitor against the proliferation, migration and invasion of lung cancer cells. MTT assay and cell colony formation assay results showed that TA25 exhibits acceptable inhibitory effect against the proliferation of lung cancer A549 cells, and the value of IC was about 17.9 μM.

Measuring and valuing health-related quality of life among children and adolescents in mainland China--a pilot study.

Background: The Child Health Utility 9D (CHU9D), a new generic preference-based health-related quality of life (HRQoL) instrument, has been validated for use in young people in both the UK and Australia. The main objectives of this study were to examine the feasibility of using a Chinese version of the CHU9D (CHU9D-CHN) to assess HRQoL and to investigate the association of physical activity, homework hours and sleep duration with HRQoL in children and adolescents in Mainland China.

Methods: Data were collected using a multi-stage sampling method from grades 4-12 students in May 2013 in Nanjing, China.

[Dietary patterns and hyperglycemia in a follow-up study in Nanjing city].

Objective: To investigate the association between dietary patterns and the risk of developing hyperglycemia in Nanjing.

Methods: Using multi-stage stratified random cluster sampling, the baseline survey was conducted on local residents older than 30 years in 7 communities from 2 urban districts from June to September 2007 in Nanjing. The total eligible subjects were 3376.

The effect of CNTs on structures and catalytic properties of AuPd clusters for H2O2 synthesis.

The structures and catalytic properties of AuPd clusters supported on carbon nanotubes (CNTs) for H(2)O(2) synthesis have been investigated by means of density functional theory calculations. Firstly, the structures of AuPd clusters are strongly influenced by CNTs, in which the bottom layers are mainly composed of Pd and the top layers are a mix of Au and Pd due to the stronger binding of Pd than Au on CNTs. Especially, it is found that O(2) adsorption on the Pd/CNTs interfacial sites is much weaker than that on the only Pd sites, which is in contrast to transition metal oxide (for example TiO(2), Al(2)O(3), CeO(2)) supported metal clusters.