Supramolecular assemblies and nanoparticle integration studied through quantitative image analysis and 3D reconstruction.

Nanoparticle incorporation into supramolecular assemblies is essential for designing hybrid nanostructures with tailored optical and structural properties. However, understanding the interactions that govern the attachment and formation of such composites remains a challenge, particularly when complex structures are involved. In this study, we explore the fabrication of quantum dot (QD)/J-aggregate composites of tetrakis(4-sulfonatophenyl)porphyrin (HTPPS), where electrostatic interactions between cysteamine-functionalized QDs and negatively charged J-aggregates of HTPPS with L-alanine play a key role in their formation.

Sulfur-Functionalized MOF via Ligand Additive-Stabilized SALE for Efficient Hg Ion Removal.

Metal-organic frameworks (MOFs) are versatile materials used in adsorption and separation. Post-synthetic modification, especially solvent-assisted linker exchange (SALE), enables precise ligand functionalization while maintaining framework integrity. However, incorporating linkers with Lewis basic sites presents challenges due to their strong coordination tendencies, which can disrupt framework stability.

Protective Behaviors Against COVID-19 and Related Factors in Korean Adults With Depressive Symptoms: Results From an Analysis of the 2020 Korean Community Health Survey.

Objective: This study evaluated protective behaviors against coronavirus disease-2019 (COVID-19) and related factors in individuals with depressive symptoms.

Methods: This cross-sectional study included data from the 2020 Korean Community Health Survey. Depressive symptoms, COVID- 19 protection behaviors, and related factors were investigated in 228,485 people.

Pd-catalyzed oxa-[4 + ] dipolar cycloaddition using 1,4-O/C dipole synthons for the synthesis of O-heterocycles.

Transition metal-catalyzed dipolar cycloaddition is one of the most efficient and powerful synthetic strategies to produce diverse heterocycles. In particular, for the construction of oxygen-containing heterocycles, which are valuable structural motifs found in pharmaceuticals and natural compounds, transition metal-catalyzed oxa-dipolar cycloaddition using an oxygen-containing dipole has emerged as a promising method. In recent years, the 1,4-O/C dipole synthons 2-alkylidenetrimethylene carbonate and 2-hydroxymethylallyl carbonate have been developed and successfully applied to palladium-catalyzed oxa-[4 + ] dipolar cycloadditions with diverse dipolarophiles.

One-Pot Synthesis of Unprotected 2-Acylpyrroles from 1,2,3Triazoles and 2-Hydroxymethylallyl Carbonates.

An efficient, tandem one-pot approach to synthesize multisubstituted 2-acylpyrroles from readily prepared -tosyl triazoles and 2-hydroxymethylallyl carbonates is reported. The reaction proceeds via Rh(II)-catalyzed O-H insertion, [3,3]-sigmatropic rearrangement, Pd(0)-catalyzed oxidative addition, intramolecular cyclization, DBU-promoted E1cB elimination, double bond isomerization, and aromatization, enabling the disconnection and formation of multiple bonds in one reactor. The approach represents a highly regioselective way to access di-, tri-, and tetra-substituted H pyrroles with high efficiency.

Rh(II)-Catalyzed C-N Bond Formation Using Enynones and N-H Imines: An Approach to Diarylmethylamines.

A Rh(II)-catalyzed furyl carbene N-H insertion reaction involving an -sp-hybridized imine is described, which represents an atom-economical route by which to access diarylmethylamine derivatives with high efficiency and broad substrate scope. An unusual reaction mechanism is proposed, in which the rhodium catalyst plays a dual role in facilitating enynone cyclization via activation and enhancement of the nucleophilicity of the NH imine.