Publications by authors named "Hiroto Funahashi"

Background: Total hip arthroplasty (THA) is an effective treatment for dysplastic hip osteoarthritis (DHOA); however, factors associated with lower limb alignment changes after THA remain unclear. This study investigated factors associated with these changes in patients undergoing THA for DHOA.

Methods: We analyzed 121 patients undergoing THA for unilateral DHOA between 2018 and 2022.

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Background: Although total hip arthroplasty (THA) post-periacetabular osteotomy (PAO) has yielded excellent short-term and mid-term outcomes, long-term implant survivorship remains unclear. This study aimed to evaluate the long-term (minimum 10 year) outcomes of THA post-PAO and assist in determining surgical indications and planning for THA post-PAO.

Methods: This study included 50 hips that underwent THA post-PAO, with a minimum follow-up of 10 years.

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Introduction: The use of navigation systems may improve the preoperative planning and outcomes of less-experienced surgeons for periacetabular osteotomies. This study aimed to evaluate the clinical outcomes of conventional and navigation-guided eccentric rotational acetabular osteotomy (ERAO).

Methods: The inclusion criteria were patients that underwent ERAO performed by less experienced surgeons (performing ERAO less than 25 cases) for hip dysplasia between January 2016 and December 2022.

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Background: The Japanese Investigation Committee classification of type B osteonecrosis of the femoral head (ONFH) should be further subdivided into types B1 and B2 based on the center of the weight-bearing area. In this study, we investigated whether there is a difference in survival rates between types B1 and B2.

Methods: This study included patients diagnosed with type B ONFH at our institution between 2010 and 2021 who either progressed to collapse or did not collapse and were followed up for at least 3 years.

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Introduction: Polypharmacy is common in older patients and associated with adverse outcomes. However, the association with outcomes in patients with intertrochanteric fractures remains unclear. This study aimed to investigate associations between polypharmacy and 1-year survival (primary outcome) and postoperative complications (secondary outcome), in older patients undergoing surgical treatment for intertrochanteric fractures.

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Introduction: Pelvic obliquity (PO) in dysplastic hip osteoarthritis (DHOA) can present as either upward or downward tilting of the affected side. This study investigated the influence of preoperative PO direction on postoperative clinical outcomes and hip-spine morphology in patients undergoing total hip arthroplasty (THA).

Materials And Methods: Data from 116 (21 men, 95 women) patients with unilateral DHOA, who underwent THA at a single institution between June 2018 and September 2023 and exhibited ≥ 2° of PO, were analyzed.

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Purpose: Accurate cup placement is challenging in total hip arthroplasty (THA) for dysplastic hip osteoarthritis (DHOA) because of the complex morphology of the acetabulum. Studies have reported good accuracy for total hip arthroplasty (THA) using computed tomography-based navigation (CTN); however, in recent years, portable navigation (PN) has become more widely applied because of its low cost and ease of use. This study aimed to compare the accuracy of portable navigation with that of CT-based navigation.

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Purpose: Muscle mass and fatty infiltration can be assessed on computed tomography (CT) images using the cross-sectional area (CSA) and computed tomography attenuation value (CTV). Femoral head collapse in osteonecrosis of the femoral head (ONFH) may affect both values. We investigated factors influencing the CSA and CTV of the periarticular muscles in patients with ONFH.

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The growth of periacetabular osteophytes with developmental dysplasia of the hip (DDH) remains unclear. This study aimed to perform a three-dimensional assessment of periacetabular osteophytes and the effects of superiorization (SP) and lateralization (LT) of the femoral head on osteophyte formation. Female (n = 105) with unilateral hip osteoarthritis due to DDH who underwent total hip arthroplasty between 2016 and 2022 were included.

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Purpose: The Japanese Investigation Committee (JIC) classification for osteonecrosis of the femoral head (ONFH) is based on the necrotic area relative to the weight-bearing surface on anteroposterior (AP) radiographs or central coronal MRI. Discrepancies exist between these methods, potentially related to the AP necrosis area. This study evaluated these discrepancies and the extent of AP necrotic lesions.

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Article Synopsis
  • The study evaluates the conjoined tendon-preserving posterior (CPP) approach in total hip arthroplasty (THA) for its clinical outcomes and complications compared to the standard posterior approach (PA).
  • A total of 83 patients were analyzed, showing that the CPP approach resulted in longer surgery times and more blood loss, but did not significantly differ in hip function scores or complication rates.
  • Both approaches had comparable success regarding complications and implant alignment, suggesting CPP could lower dislocation rates, but caution is needed due to potential nerve issues.
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Purpose: Factors affecting direction of pelvic obliquity (PO) in dysplastic hip osteoarthritis (DHOA) remains unclear. This retrospective cohort study evaluates morphological characteristics, spinal alignment, and hip function in patients with unilateral DHOA.

Methods: Between 2018 and 2022, 104 patients with unilateral DHA were enrolled.

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Article Synopsis
  • Eccentric rotational acetabular osteotomy is used to prevent hip osteoarthritis from developmental dysplasia (DDH), but the differences in acetabular coverage between genders in DDH patients are poorly understood.
  • The study aimed to identify these differences in acetabular coverage and pelvic morphology between males and females, as well as how the rotation of certain pelvic bones relates to acetabular coverage.
  • The research involved analyzing the preoperative data of 100 patients who underwent the surgery, focusing on various measurements from radiographs and CT scans to compare the anatomical features of male and female patients with DDH.
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Purpose: This study aimed to identify factors related to collapse progression in Japanese Investigation Committee classification type B osteonecrosis of the femoral head (ONFH) and to identify patients who would benefit from surgical treatment.

Methods: This study included 41 patients (56 hips) with type B ONFH with a minimum follow-up of three years. Based on a ≥ 3 mm collapse progression in ONFH, we categorised patients into two groups: collapse progression and no collapse progression.

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Aim: Advanced glycation end-products (AGEs) are irreversibly and heterogeneously formed compounds during the non-enzymatic modification of macromolecules, such as proteins. Aging and lifestyle habits, such as high-fat and high-protein diets, and smoking, promote AGEs accumulation. This study aimed to investigate the relationship between fall risk and AGEs in community-dwelling older adults.

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Achondroplasia (ACH) is a skeletal dysplasia characterized by short-limbed short stature caused by the gain-of-function mutations in the fibroblast growth factor receptor 3 (FGFR3) gene. Activated FGFR3, which is a negative regulator of bone elongation, impairs the growth of long bones and the spinal arch by inhibiting chondrocyte proliferation and differentiation. Most patients with ACH have spinal canal stenosis in addition to short stature.

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Article Synopsis
  • - The study focuses on the importance of muscle quality, measured by CT imaging, over muscle mass when assessing physical function in patients with hip osteoarthritis (HOA) undergoing total hip arthroplasty (THA).
  • - Researchers analyzed the impact of mid-thigh quadriceps cross-sectional area (CSA) and CT attenuation values (CTV) on preoperative and postoperative functional scores in 62 HOA patients.
  • - Results showed that while muscle CSA did not correlate with functional scores, higher muscle quality (CTV) was linked to better postoperative outcomes, emphasizing the relevance of muscle quality in recovery.
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It is often difficult to achieve adequate bone coverage of the cup in total hip arthroplasty in cases of severe developmental dysplasia of the hip (DDH). This study aimed to evaluate the relationship between subluxation percentage of Crowe classification and cup center-edge (cup-CE) angle to investigate whether subluxation percentage according to the Crowe classification is a useful indicator for cementless cup placement. Cementless cup placement was simulated in 77 women with DDH in 91 hips (Crowe I, 35 hips; Crowe II, 35 hips; and Crowe III, 21 hips) using computed tomography-based computer simulation software.

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Objective: The association between knee osteoarthritis (OA) and miRNAs has been widely reported. However, the utility of miRNAs as predictors of knee osteoarthritis (KOA) progression in longitudinal studies has not been reported. We aimed to identify circulating miRNAs (c-miRNAs) associated with KOA progression in the general population and to examine their potential use as predictors of KOA progression.

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Unlabelled: This study investigated the impact of osteoporosis treatment on the prognosis of patients with periprosthetic femoral fracture (PPF) following femoral neck fracture (FNF). Our results suggested an association between osteoporosis treatment and potentially improved survival prognosis in patients who underwent surgery for PPF. These results imply that osteoporosis treatment may have a beneficial effect on patient outcomes.

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Article Synopsis
  • The study investigated the factors causing lateralization (shifting to the side) and superiorization (shifting upwards) of the femoral head following a surgical procedure called eccentric rotational acetabular osteotomy (ERAO) in patients with hip dysplasia.
  • It involved 52 patients, measuring femoral head positions using CT scans and analyzing how osteotomy angles correlated with changes in position and clinical outcomes, specifically looking at Japanese Orthopaedic Association (JOA) scores.
  • Results indicated that larger osteotomy angles lead to higher risks of femoral head shifting, highlighting the importance for surgeons to carefully manage the angles during the ERAO procedure to achieve optimal results.
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Background: To investigate muscle volume changes in all body regions after total hip arthroplasty (THA) with dual-energy X-ray absorptiometry (DEXA), and determine the positive effects of THA for systemic muscle atrophy in patients with hip osteoarthritis (HOA).

Methods: In total, 116 patients with a mean age of 65.8 (45-84) years who had undergone THA for unilateral HOA were included in this study.

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Bony impingement, especially in the anterior inferior iliac spine (AIIS) after total hip arthroplasty (THA), may cause dislocation. However, the influence of AIIS characteristics on bony impingement after THA is not fully understood. Thus, we aimed to determine the morphological characteristics of AIIS with developmental dysplasia of the hip (DDH) and primary osteoarthritis (pOA) and to evaluate its effect on range of motion (ROM) after THA.

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Introduction: The Geriatric Nutritional Risk Index (GNRI) is an objective nutritional status assessment tool used for predicting mortality risk in hospitalized patients. However, it is unclear whether GNRI reflects short-term mortality for hip fracture patients after surgery. We examined the usefulness of the nutritional status assessed by the GNRI and identified cutoff scores that predict mortality risk.

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Blood pressure changes around cement insertion during total hip arthroplasty have been investigated; however, there is little agreement regarding whether a similar phenomenon occurs during hemiarthroplasty in the elderly under spinal anaesthesia. Therefore, our objective was to examine blood pressure around cement insertion during hemiarthroplasty in the elderly. For this retrospective, single-centre, case series study, we identified 430 hips of patients aged >65 years who underwent cemented hemiarthroplasty under spinal anaesthesia from January 2010 to August 2018.

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