J Dev Orig Health Dis
September 2025
This study aimed to explore the associations between weight gain during infancy with pre-pregnant body mass index (BMI) later in life, focusing on risks of being overweight or underweight. A retrospective cohort study was conducted using data from women ( = 1082) who visited the National Center for Child Health and Development between 2017 and 2021. The participants provided their Maternal and Child Health Handbook, which included records of their own birthweight and weight gain from birth to 1, 3, and 6 months.
View Article and Find Full Text PDFIn Japan, maintenance tocolysis has been conventionally administered. The current study aimed to identify the annual trends in the prolonged administration of ritodrine hydrochloride and its differences in terms of region and type of facility. This study used data from the Japanese Diagnosis Procedure Combination inpatient database, and the survey included women with premature labor or threatened premature delivery based on the International Statistical Classification of Diseases and Related Health Problems, 10th Revision, codes.
View Article and Find Full Text PDFAfter the mid-second trimester, women with intrauterine fetal death (IUFD) are managed with cervical dilation and vaginal gemeprost or intravenous oxytocin. In women with IUFD complicated by placenta previa, unneglectable concerns about massive bleeding during the procedure pose a burden on healthcare providers. Although a standardized management remains unestablished, the treatment options for IUFD complicated by placenta previa include cesarean section, gemeprost, and intravenous oxytocin, and such procedures follow uterine artery embolization.
View Article and Find Full Text PDFArch Gynecol Obstet
August 2024
Background/aim: We demonstrated that AT1 and AT2 are expressed and both pathways balance the renin-angiotensin system in endometriosis. MAS1, a specific receptor of angiotensin (1-7), opposes AT1 pathway-associated tissue remodelling. It is not known whether MAS1 has an effect on the pathogenesis of endometriosis or not.
View Article and Find Full Text PDFBackground: Although rodent decidual mast cells (MCs) reportedly play an important role in implantation and placenta formation, the characterization of human decidual MCs has been not well clarified. The aims of this study were to investigate the distribution and characteristics of MCs in human decidua and to establish a culture system for decidua-derived MCs.
Methods: Decidual tissues were obtained from patients who underwent a legal elective abortion (6th week to 9th week of pregnancy), and decidual MCs were enzymatically dispersed.
J Obstet Gynaecol Res
July 2016
Aim: The anti-β2-GPI antibody (aβ2-GPIAb) has been detected in recurrent fetal loss with strong pathogenic activity. The effects of aβ2-GPIAb on cytokine production and aβ2-GPIAb binding sites in first-trimester trophoblast cells were evaluated.
Methods: First-trimester trophoblast cells were cultured in 24-well tissue culture plates with immunoglobulin G (IgG) obtained from aβ2-GPIAb-positive and aβ2-GPIAb-negative serum.