Publications by authors named "Hiroki Yamaura"

Aims: This study aimed to assess clinical risks and coronary atherosclerotic burden in patients with chronic coronary syndrome (CCS) stratified by pericoronary artery adipose tissue (PCAT) composition and epicardial adipose tissue volume (EAV).

Methods And Results: We retrospectively included 410 CCS patients who underwent coronary computed tomography angiography. Patients were divided into four groups based on an EAV index ≥ 73.

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Aortic arch plaque (AAP) morphology and complexity can serve as markers of atherosclerotic cardiovascular disease. This study investigated 1) the diagnostic value of the thoracic aortic calcification (TAC) score for detecting AAP and large complex AAP and 2) the prognostic significance of TAC in patients with chronic coronary syndrome (CCS). The predictors of AAPs with large (≥ 4 mm in thickness) and complex (ulcerated or protruded) morphologies were evaluated in 412 symptomatic patients with CCS who underwent coronary computed tomography angiography and simultaneous assessment of the aortic arch.

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Aims: This study aims to investigate the association between left ventricular diastolic dysfunction (LVDD) and epicardial adipose tissue (EAT) accumulation in patients with chronic coronary syndrome (CCS) and preserved left ventricular ejection fraction (LVEF).

Methods And Results: The study included 314 patients with preserved LVEF who underwent coronary computed tomographic angiography (CCTA) and thoracic tissue Doppler echocardiography (TTDE). The EAT volume was measured using CCTA.

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Article Synopsis
  • The study explores the connection between diabetes mellitus (DM), low-attenuation plaque (LAP) volume, and cardiovascular events in patients suspected of having coronary artery disease (CAD).
  • It categorized 530 patients based on the presence of metabolic syndrome (MetS) and DM and found that those with DM, regardless of MetS status, had the highest incidence of major cardiovascular events (MACE).
  • The results emphasize that DM is a stronger independent predictor of MACE than MetS, with significant implications for patient treatment and risk assessment.
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Background: There is limited knowledge regarding whether an elevated triglyceride glucose (TyG) index can serve as a prognostic marker for mortality and cardiovascular outcomes, independent of diabetes mellitus (DM) and plaque burden, in patients with chronic coronary syndrome (CCS).

Methods: Patients with CCS (n = 684) were categorized into subgroups based on the presence of DM, and patients without DM were further divided into two groups based on presence or absence of an elevation of TyG index >8.8.

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Aim: Wide volume scan (WVS) coronary computed tomography angiography (CCTA) enables aortic arch visualization. This study assessed whether the thoracic aortic plaque burden (TAPB) score can predict major cardiovascular adverse events (MACE) in addition to and independently of other obstructive coronary artery disease (CAD) attributes.

Methods: This study included patients with suspected CAD who underwent CCTA (n=455).

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Background: This study aimed to investigate the association between the extent and severity of coronary atherosclerosis, epicardial adipose tissue (EAT) accumulation, and left ventricular (LV) global longitudinal strain (GLS) in patients with preserved LV ejection fraction (LVEF) and without LV regional wall motion abnormalities.

Methods: This study included 169 preserved LVEF patients without LV wall motion abnormalities who underwent coronary computed tomography (CT) angiography for the assessment of suspected coronary artery disease (CAD). The segment stenosis score (SSS) and segment involvement score (SIS) were calculated to evaluate CAD extent.

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Background: Wide-volume scanning with 320-row multidetector computed tomography coronary angiography (CTCA-WVS) enables the assessment of the aortic arch plaque (AAP) morphology and coronary arteries without requiring additional contrast volume. This study aimed to investigate the prevalence of AAPs and their association with coronary artery disease (CAD) and major adverse cardiovascular events (MACEs) in patients who underwent CTCA-WVS.

Methods: This study included 204 patients without known CAD (mean age, 65 years; 53% men) who underwent CTCA-WVS.

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Background: Although epicardial adipose tissue (EAT) is associated with coronary artery disease (CAD), it is unclear whether EAT volume (EAV) can be used to diagnose high-risk coronary plaque burden associated with coronary events. This study aimed to investigate (1) the prognostic impact of low-attenuation non-calcified coronary plaque (LAP) burden on patient level analysis, and (2) the association of EAV with LAP volume in patients without known CAD undergoing coronary computed tomography angiography (CCTA).

Materials And Methods: This retrospective study consisted of 376 patients (male, 57%; mean age, 65.

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