The role of iron biomarkers in predicting type 2 Diabetes: An international, multi-cohort Study.

Aims: We investigated whether adding iron biomarkers into existing type 2 diabetes risk models improves risk prediction.

Methods: Data from three population-based cohorts were used; CoLaus|PsyCoLaus in Switzerland (5250 participants, 54.9 % females, mean age± standard deviation 51.

Local Climate Change Adaptation under the Lenses of Public Health: A Case Study from Porto, Portugal.

Introduction: Climate change is a pressing public health issue. Urban populations, especially in coastal areas, are highly vulnerable. As climate change progresses, local adaptation becomes increasingly important.

Residential exposure to green and blue spaces over childhood and cardiometabolic health outcomes: The generation XXI birth cohort.

Evidence on the effects of green and blue spaces on childhood cardiometabolic health is inconsistent and mostly cross-sectional. We assessed the associations of green and blue spaces exposure at birth 4, 7, and 10 years (to identify vulnerable periods of exposure) and as longitudinal trajectories (to identify the longitudinal effect over time) with cardiometabolic outcomes at 10 years. Among 4669 participants from a population-based birth cohort, we assessed the residential normalized difference vegetation index (NDVI) and distance to urban green and blue spaces at each time point using geographic information systems and standardized by dividing the observed value by the standard deviation.

Safety, Efficacy, and Pharmacokinetics of Daily Optimized Doses of Rifampicin for the Treatment of Tuberculosis: A Systematic Review and Bayesian Network Meta-Analysis.

Background: Higher than standard doses of rifampicin could improve the treatment outcome of drug-susceptible tuberculosis (TB) without compromising the safety of patients.

Methods: We performed a systematic review of prospective clinical studies including adults with pulmonary and extrapulmonary TB receiving rifampicin doses above 10 mg/kg/day. We extracted the data on overall adverse events (AE), hepatic AE, sputum culture conversion (SCC) at week 8, recurrence, mortality, and pharmacokinetics.

Maternal caffeine intake during pregnancy and the risk of childhood asthma by 10 years of age-Evidence from The Generation XXI birth cohort study.

Background: We aimed to investigate the association between maternal caffeine intake during pregnancy and asthma in children by 10 years of age.

Methods: We considered 5585 mother-child pairs enrolled in a population-based birth cohort. Consumption of regular and decaffeinated coffee, black and green tea, and cola beverages before and during pregnancy was obtained through face-to-face interviews within 72 h after giving birth, and total caffeine intake (mg/day) was estimated.

A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children.

Background/objective: There is limited knowledge on how diet affects the epigenome of children. Ultra-processed food (UPF) consumption is emerging as an important factor impacting health, but mechanisms need to be uncovered. We therefore aimed to assess the association between UPF consumption and DNA methylation in children.

Transfer learning in spirometry: CNN models for automated flow-volume curve quality control in paediatric populations.

Problem: Current spirometers face challenges in evaluating acceptability criteria, often requiring manual visual inspection by trained specialists. Automating this process could improve diagnostic workflows and reduce variability in test assessments.

Aim: This study aimed to apply transfer learning to convolutional neural networks (CNNs) to automate the classification of spirometry flow-volume curves based on acceptability criteria.

Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis.

Objectives: To investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study.

Design: Pooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined.

Setting: Children aged 0-18 years from 26 European birth cohorts.

Socioeconomic disparities in changes to preterm birth and stillbirth rates during the first year of the COVID-19 pandemic: a study of 21 European countries.

Background: Despite concerns about worsening pregnancy outcomes resulting from healthcare restrictions, economic difficulties and increased stress during the COVID-19 pandemic, preterm birth (PTB) rates declined in some countries in 2020, while stillbirth rates appeared stable. Like other shocks, the pandemic may have exacerbated existing socioeconomic disparities in pregnancy, but this remains to be established. Our objective was to investigate changes in PTB and stillbirth by socioeconomic status (SES) in European countries.

Corrigendum: Merging Academy and Healthcare in the Public Health Training of Medical Students.

[This corrects the article DOI: 10.1186/s40985-020-00146-1.].

The association between probable post-COVID-19 condition and sleep-related parameters: a longitudinal study of non-hospitalised patients.

The long-term effects of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection on sleep remain poorly known. We evaluated the association between probable post-COVID-19 condition and changes in sleep quality and quantity before and after SARS-CoV-2 infection in a consecutive sample of non-hospitalized adults. Individuals were identified with SARS-CoV-2 infection in 2020 at the central laboratory of a tertiary hospital in Porto and followed as outpatients.

Obstetric Interventions Among Native and Migrant Women: The (Over)use of Episiotomy in Portugal.

Episiotomy, defined as the incision of the perineum to enlarge the vaginal opening during childbirth, is one of the most commonly performed surgical interventions in the world. We aimed to determine if migrant status is associated with episiotomy, and if individual characteristics mediate this association. We analyzed data from the Bambino study, a national, prospective cohort of migrant and native women giving birth at a public hospital in mainland Portugal between 2017 and 2019.

Prevalence of Parental Violent Discipline Toward Children: Findings From A Portuguese Population.

Despite recognizing the detrimental impact of parental violence on children's mental and physical health throughout their lives, violence remains an all-too-real part of life for many children around the globe. However, data on the child-reported prevalence of experienced family violence are scarce and primarily based on parental reports. This study aimed to broaden the body of evidence and measure the lifetime prevalence of child-reported experience of violent disciplinary practices perpetrated by parents and to identify its associated sociodemographic and economic factors.

Parental infertility and offspring cardiometabolic trajectories: a pooled analysis of three European cohorts.

Objective: To assess whether parental infertility is associated with differences in cardiometabolic trajectories in offspring.

Design: Pooled observational analysis in three prospective cohorts.

Setting: Three nationwide pregnancy cohorts.

Component-resolved diagnosis in childhood and prediction of asthma in early adolescence: A birth cohort study.

Introduction: Component-resolved diagnosis (CRD) has been decisive in exploring the mechanisms of IgE sensitization, but the predictive ability to detect asthma has not been addressed. We aim to develop and evaluate the performance of a personalized predictive algorithm for asthma that integrates information on allergic sensitization using CRD.

Methods: One thousand one hundred one twenty-five children from the Generation XXI birth cohort were randomly selected to perform a screening test for allergic sensitization and a subsample was characterized using CRD against 112 allergen components.

Prediction of movement difficulties at 5 years from parent report at 2 years in children born extremely preterm.

Aim: To assess the predictive validity of parent-reported gross motor impairment (GMI) at age 2 years to detect significant movement difficulties at age 5 years in children born extremely preterm.

Method: Data were from 556 children (270 males, 286 females) born at less than 28 weeks' gestation in 2011 to 2012 in 10 European countries. Parent report of moderate/severe GMI was defined as walking unsteadily or unable to walk unassisted at 2 years corrected age.

Incarceration history is associated with HIV infection among community-recruited people who inject drugs in Europe: A propensity-score matched analysis of cross-sectional studies.

Aims: We measured the association between a history of incarceration and HIV positivity among people who inject drugs (PWID) across Europe.

Design, Setting And Participants: This was a cross-sectional, multi-site, multi-year propensity-score matched analysis conducted in Europe. Participants comprised community-recruited PWID who reported a recent injection (within the last 12 months).

Variation in follow-up for children born very preterm in Europe.

Background: Children born very preterm (<32 weeks of gestation) face high risks of neurodevelopmental and health difficulties compared with children born at term. Follow-up after discharge from the neonatal intensive care unit is essential to ensure early detection and intervention, but data on policy approaches are sparse.

Methods: We investigated the characteristics of follow-up policy and programmes in 11 European countries from 2011 to 2022 using healthcare informant questionnaires and the published/grey literature.

The influence of the Great Recession on perinatal health-an ecological study on the trend changes and regional differences in Portugal.

Background: Few studies examine the relationship between socioeconomic factors and trends in mortality in high-income European countries. Due to the lack of regional-level data, most recent studies on social inequality in Portugal do not investigate regional differences. This study analyses time trends and regional disparities in the evolution of perinatal mortality (PMR) and infant mortality (IMR) associated with demographic and socioeconomic indicators following Portugal's 2008 economic and financial crisis.