Publications by authors named "Hasan Alarouri"
Purpose: Atrial fibrillation (AF) is the most common chronic cardiac arrhythmia that increases the risk of stroke, primarily due to thrombus formation in the left atrial appendage (LAA). Left atrial appendage occlusion (LAAO) devices offer an alternative to oral anticoagulation for stroke prevention. However, the complex and variable anatomy of the LAA presents significant challenges to device design and deployment.
View Article and Find Full Text PDFSurveillance imaging at 45 to 90 days after transcatheter left atrial appendage occlusion device implantation with transesophageal echocardiography (TEE) or cardiac computed tomography (CT) is recommended to assess device position and the presence of device-related complications such as device-related thrombus (DRT) or peridevice leak. Detection of DRT is associated with a significantly increased risk of a stroke or systemic embolization event within 6 months of detection. Nonetheless, there is significant variability in detection of DRT as a result of timing, frequency, and imaging modality used for surveillance.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate the consistency of interpreting cardiac CT scans for hypoattenuated thickening (HAT) and peridevice leak (PDL) after left atrial appendage closure (LAAC) with the Watchman FLX device.
- In a multicenter study involving 100 anonymized CT scans, both an experienced and a novice rater independently assessed readings, showing substantial agreement, particularly in identifying high-grade HAT and distal patency, while some specific measures proved less reliable.
- The conclusion indicates that even with minimal training, high inter- and intra-rater reliability was achieved for most interpretations, suggesting that future research will further investigate the implications of these findings.
Article Synopsis
- Short-term antithrombotic therapy is necessary after left atrial appendage occlusion (LAAO) to prevent device-related thrombosis, but there's a significant risk of bleeding in these patients.
- A study involving 592 patients showed that 14% experienced early bleeding within 3 months post-discharge, which is linked to a nearly doubled risk of all-cause mortality.
- Independent predictors of early bleeding included previous intracranial bleeding, specific types of atrial fibrillation, and certain clinical scores, indicating a need for improved management strategies for patients undergoing LAAO.
Objective: In recent years, patients with celiac disease (CeD) have been reported to have a high prevalence of fatty liver and metabolic syndrome. We conducted a systematic review and meta-analysis to assess the prevalence of fatty liver and metabolic syndrome in patients with CeD and effect of gluten-free diet in them.
Methods: The PubMed, Embase and the Cochrane Library databases were searched for original studies upto November 18, 2022.
Background: The hemodynamic effects of transcatheter left atrial appendage occlusion (LAAO) remain unclear.
Objective: We sought to assess the effect of LAAO on invasive hemodynamics and their correlation with clinical outcomes.
Methods: We recorded mean left atrial pressure (mLAP) before and after device deployment.
Background: Acute ischemic stroke complicates 2% to 3% of transcatheter aortic valve replacements (TAVRs). This study aimed to identify the aortic anatomic correlates in patients after TAVR stroke.
Methods And Results: This is a single-center, retrospective study of patients who underwent TAVR at the Mayo Clinic between 2012 and 2022.
Device-Related Thrombus After Left Atrial Appendage Occlusion: Clinical Impact, Predictors, Classification, and Management.
JACC Cardiovasc Interv
November 2023
Despite the unprecedented advances in the left atrial appendage occlusion field, device-related thrombus (DRT) remains an unresolved issue with the therapy. This paper aims to provide a state-of-the-art review of the literature on the incidence, clinical impact, predictors and management of DRT and propose a novel classification of DRT and hypoattenuated thickening.
View Article and Find Full Text PDFBackground Patient-reported outcome measures have been shown to have important prognostic value after various cardiac interventions. We assessed the association between the change in Kansas City Cardiomyopathy Questionnaire 12 (KCCQ-12) score after transcatheter aortic valve replacement and mortality. Methods and Results We included patients who underwent transcatheter aortic valve replacement at Mayo Clinic between February 2012 to June 2022 and who completed a KCCQ-12 before and 30 to 45 days after the procedure.
View Article and Find Full Text PDFPredictors of hemodynamic response to mitral transcatheter edge-to-edge repair.
Catheter Cardiovasc Interv
May 2023
Background: Improvement in left atrial pressure (LAP) during transcatheter edge-to-edge repair (TEER) is associated with improved outcomes. We sought to investigate the predictors of optimal hemodynamic response to TEER.
Methods: We identified patients who underwent TEER at Mayo Clinic between May 2014 and February 2022.