Dual-path off-axis digital holographic microscopy (DHM) has been effectively used for quantitative phase imaging applications. However, challenges are involved in its development because of complex and bulky optical systems, phase aberrations, and low temporal stability. In this work, a common-path off-axis DHM is proposed based on the lateral shearing of object-scattered wavefronts.
View Article and Find Full Text PDFThe global antimicrobial resistance crisis has stimulated the development of innovative therapeutics. Methicillin-resistant Staphylococcus aureus (MRSA), a critical pathogen responsible for skin and soft tissue infections. MRSA biofilms exhibit greater resistance to antibiotics compared to planktonic cells.
View Article and Find Full Text PDFCancer is a significant cause of death after cardiovascular disease. The genomic, epigenetic and environmental factors have been found to be the risk factor for the disease. The most important genes that develop cancer are oncogenes and tumor suppressor genes.
View Article and Find Full Text PDFOncogenic metabolic reprogramming impacts the abundance of key metabolites that regulate signaling and epigenetics. Metabolic vulnerability in the cancer cell is evident from the Warburg effect. The research on metabolism in the progression and survival of breast cancer (BC) is under focus.
View Article and Find Full Text PDFMicroRNAs (miRNAs) negatively affect gene expression by binding to their specific mRNAs resulting in either mRNA destruction or translational repression. The aberrant expression of various miRNAs has been associated with a number of human cancer. Oncogenic or tumor-suppressor miRNAs regulate a variety of pathways involved in the development of breast cancer (BC), including cell proliferation, apoptosis, metastasis, cancer recurrence, and chemoresistance.
View Article and Find Full Text PDFThis paper discusses an improved technique for bandwidth-efficient and secure transmission of medical records over simulated orthogonal frequency division multiplexing (OFDM)-based Worldwide Interoperability for Microwave Access (WiMAX)/IEEE 802.16 physical layer. Medical data compaction along with security has been achieved by embedding electrocardiogram (ECG) data into Haar wavelet coefficients of an x-ray image that is transmitted over the channel.
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