Publications by authors named "Hanin Moh'd Kalloush"
Article Synopsis
- Matrix metalloproteinases (MMPs) are enzymes that can break down proteins in the extracellular matrix and are categorized into six groups based on their functions.
- MMPs play a significant role in various biological processes, including cancer development and metastasis, making them important targets for cancer treatment.
- Advances in research techniques have led to the creation of more selective second-generation MMP inhibitors, improving their effectiveness as potential anticancer drugs compared to earlier broad-spectrum inhibitors.
Molecular toxicological alterations in the mouse hearts induced by sub-chronic thiazolidinedione drugs administration.
Fundam Clin Pharmacol
February 2022
Thiazolidinediones are well-known anti-diabetic drugs. However, they are not widely used due to their cardiotoxic effects. Therefore, in this study, we aimed to determine the molecular toxicological alterations induced in the mouse hearts after thiazolidinedione administration.
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