Publications by authors named "Hani Cheikh Sleiman"
This paper presents an open-source pipeline for simulating flow and flow-related processes in (embedded) tubular structures. Addressing a gap in computational fluid dynamics (CFD) and simulation sciences, it facilitates the transition from raw three-dimensional imaging, graph networks or computer aided design (CAD) models of tubular objects to refined, simulation-ready meshes. This transition, traditionally labour-intensive, is streamlined through a series of innovative steps that include surface mesh processing, centre-line construction, anisotropic mesh generation and volumetric meshing, leading to finite element method (FEM) simulations.
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- - The placenta is essential for pregnancy, handling oxygen and nutrient exchange, with complications like fetal growth restriction linked to its vascular structure issues, emphasizing the need for early detection of placental health.
- - Current computational models of placental vasculature lack control over crucial features like branching angles, which are necessary for predicting dysfunction, leading to the development of a new generative algorithm that allows for customizable placental vascular modeling.
- - This novel algorithm is based on physiological principles and uses key metrics to create realistic placental structures, enhancing research into how variations in structure can affect placental function and health.