One year monitoring of calcium release from an experimental composite containing calcium phosphate particles.

Introduction: Ca release from specimens made of a composite containing dicalcium phosphate dihydrate particles (CaHPO.2HO, dicalcium phosphate dihydrate [DCPD]) was followed during 1 year.

Methods: Specimens were individually immersed in deionized water ( = 3).

Ion-releasing restorative materials and dentin remineralization: Current strategies and future perspectives.

Histological studies on carious dentin have identified distinct layers with unique characteristics, leading to the development of minimally invasive restorative strategies. The conservative nature of these approaches has driven the advancement of ion-releasing materials designed to promote dentin remineralization not only by enhancing mineral content but also by restoring the functional properties of the affected tissue. In this context, the remineralizing potential of glass ionomer cements, calcium silicate-based cements, and ion-releasing resin-based composites has been the focus of extensive research.

Variables affecting ion release from resin-based materials containing calcium orthophosphate particles.

Objectives: To investigate the influence of experimental variables on Ca release from experimental resin-based materials containing dicalcium phosphate dihydrate (DCPD) particles.

Methods: Experimental materials were prepared, both with BisGMA and TEGDMA and either 25 % or 50 % DCPD (by volume). Ca release in deionized water (DW) was quantified using induced coupled plasma-optical emission spectrometry (ICP-OES, n = 3) according to the variables (1) frequency of DW renewal (weekly, biweekly, monthly or no renewal in 8 weeks), (2) volume of DW (5 mL, 10 mL or 50 mL) and (3) specimen dimensions (in mm, 9×2, 10x1, 5×4 or 5×1).

Physicochemical characterization of experimental resin-based materials containing calcium orthophosphates or calcium silicate.

Objective: To evaluate experimental dimethacrylate-based materials containing calcium orthophosphates or calcium silicate particles in terms of their optical, mechanical and Ca release behaviour.

Methods: Dicalcium phosphate dihydrate (DCPD), hydroxyapatite (HAp), beta-tricalcium phosphate (β-TCP) or calcium silicate (CaSi) particles were added to a photocurable BisGMA/TEGDMA resin (1:1 in mols) at a 30 vol% fraction. Materials containing silanized or non-silanized barium glass particles were used as controls.

Effect of a calcium silicate cement and experimental glass ionomer cements containing calcium orthophosphate particles on demineralized dentin.

Objective: The study aims to evaluate the effect of a glass ionomer cement (GIC; Fuji 9 Gold Label, GC) with added calcium orthophosphate particles and a calcium silicate cement (CSC; Biodentine, Septodont) regarding ion release, degradation in water, mineral content, and mechanical properties of demineralized dentin samples.

Methods: GIC, GIC + 5% DCPD (dicalcium phosphate dihydrate), GIC + 15% DCPD, GIC + 5% β-TCP (tricalcium phosphate), GIC + 15% β-TCP (by mass), and CSC were evaluated for Ca/Sr/F release in water for 56 days. Cement mass loss was evaluated after 7-day immersion in water.

Effect of calcium orthophosphate particle size and CaP:glass ratio on optical, mechanical and physicochemical characteristics of experimental composites.

Objective: Evaluate light transmittance (%T), color change (ΔE), degree of conversion (DC), bottom-to-top Knoop microhardness (KHN), flexural strength (BFS) and modulus (FM), water sorption/solubility (WS/SL) and calcium release of resin composites containing different dicalcium phosphate dihydrate (DCPD)-to-barium glass ratios (DCPD:BG) and DCPD particle sizes.

Methods: Ten resin-based composites (50 vol% inorganic fraction) were prepared using BG (0.4 µm) and DCPD particles (12 µm, 3 µm or mixture) with DCPD:BG of 1:3, 1:1 or 3:1.

Exposure to lipopolysaccharide and calcium silicate-based materials affects the behavior of dental pulp cells.

This study assessed the cell viability, cytokine production, and mineralization potential of human dental pulp cells (hDPCs) after exposure to lipopolysaccharide (LPS) and application of calcium silicate-based materials (CSBM). Characterization of the CSBM was performed by infrared spectroscopy (n = 3). Extracts of Bio-C Repair, Biodentine, Cimmo HD, and MTA Repair HP were prepared and diluted (1:1, 1:4, and 1:16).

Response of periodontal ligament stem cells to lipopolysaccharide and calcium silicate-based materials.

This study was conducted to assess the in vitro response of human periodontal ligament stem cells (hPDLSCs) to bacterial lipopolysaccharide (LPS) activation and application of three calcium silicate-based materials (CSBM): Bio-C Sealer, MTA Fillapex and Cimmo HP. Characterization of the CSBM was performed by FTIR (n = 3). Extracts of Bio-C Sealer, MTA Fillapex and Cimmo HP were prepared and diluted (1:1, 1:4 and 1:16).

Effect of calcium orthophosphate: Reinforcing glass ratio and prolonged water storage on flexural properties of remineralizing composites.

Objectives: To compare the effects of replacing reinforcing barium glass particles by DCPD (dicalcium phosphate dihydrate), as opposed to simply reducing glass filler content, on composite flexural properties and degree of conversion (DC). On a second set of experiments, composites with different "DCPD: glass" ratios were exposed to prolonged water immersion to verify if the presence of DCPD particles increased hydrolytic degradation.

Methods: Two series of composites were prepared: 1) composites with total inorganic content of 50 vol% and "DCPD: glass" ratios ranging from zero (glass only) to 1.

In vitro remineralization of artificial enamel caries with resin composites containing calcium phosphate particles.

The aim of the study was to evaluate the effect of experimental composites containing dicalcium phosphate dihydrate (DCPD) on remineralization of enamel lesions. Five resin-based composites containing equal parts (in mols) of bisphenol-A glycidyl dimethacrylate (BisGMA), triethylene glycol dimethacrylate (TEGDMA), and 60 vol % of fillers were manipulated. Filler phase was constituted by silanized barium glass and 0, 10, or 20 vol % of DPCD particles, either functionalized (F) or nonfunctionalized (NF) with TEGDMA.

Development of calcium phosphate/ethylene glycol dimethacrylate particles for dental applications.

This study describes the synthesis of dicalcium phosphate dihydrate (DCPD) particles in the presence of different ethylene glycol dimethacrylates (EGDMA, ethylene glycol/EG units: 1, 2, 3 or 4) at two monomer-to-ammonium phosphate molar ratios (1:1 and 2:1), as a strategy to develop CaP-monomer particles with improved interaction with resin matrices. Particles displaying high surface areas and organic contents were added to a photocurable BisGMA-TEGDMA resin and the resulting materials were tested for degree of conversion (DC), biaxial flexural strength (BFS), flexural modulus, and ion release. Data were subjected to one-way ANOVA or Kruskal-Wallis/Dunn test (alpha: 0.