Kinematically aligned total knee arthroplasty is as effective in severe varus deformities as in mild deformities.

Purpose: This study compares the clinical outcomes and radiological measures of kinematic alignment total knee arthroplasty (KA-TKA) in patients with severe knee deformities to those with mild varus.

Methods: This retrospective cohort study included 145 patients with <10° varus malalignment and 145 patients with >10° varus. All cases underwent KA-TKA performed by a single surgeon using the same techniques between 2015 and 2022.