Publications by authors named "Hai-Qin Lou"
Application of Genetic Origin Analysis of Copy Number Variations in Non-Invasive Prenatal Testing.
Prenat Diagn
January 2025
Article Synopsis
- The study evaluated the use of copy number variation (CNV) origin analysis in non-invasive prenatal testing (NIPT) to enhance its clinical application, involving over 35,000 patients from January 2019 to March 2023.
- Out of the pregnancies tested, 109 showed significant CNV results, with a majority being maternal/foetal CNVs; findings indicated that many of these abnormalities were small and had low penetrance.
- The diagnostic accuracy differed significantly between prenatal diagnoses for foetal CNVs compared to maternal/foetal CNVs, highlighting the potential effectiveness of NIPT in identifying genetic abnormalities in pregnancies.
Pelvic floor dysfunction and electrophysiology in postpartum women at 6-8 weeks.
Front Physiol
May 2023
To investigate the incidence of pelvic floor dysfunction (PFD) and electrophysiological indicators in postpartum women at 6-8 weeks and explore the influence of demographic characteristics and obstetric factors. A survey questionnaire collected information about the conditions of women during their pregnancy and puerperal period and their demographic characteristics; pelvic organ prolapse quantitation (POP-Q) and pelvic floor muscle electrophysiology (EP) examination were conducted in postpartum women at 6-8 weeks. Vaginal delivery was a risk factor for anterior pelvic organ prolapse (POP) (OR 7.
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